2-Chloroethyl ethyl sulfide

Suppliers

Names

[ CAS No. ]:
693-07-2

[ Name ]:
2-Chloroethyl ethyl sulfide

[Synonym ]:
MFCD00000979
EINECS 211-742-1
1-chloro-2-ethylsulfanylethane

Chemical & Physical Properties

[ Density]:
1.07

[ Boiling Point ]:
156-157 °C

[ Molecular Formula ]:
C4H9ClS

[ Molecular Weight ]:
124.63200

[ Flash Point ]:
52 °C

[ Exact Mass ]:
124.01100

[ PSA ]:
25.30000

[ LogP ]:
1.97830

[ Index of Refraction ]:
1.4875-1.4895

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WQ3250000
CHEMICAL NAME :
Sulfide, chloroethyl ethyl
CAS REGISTRY NUMBER :
693-07-2
BEILSTEIN REFERENCE NO. :
0635672
LAST UPDATED :
199706
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C4-H9-Cl-S
MOLECULAR WEIGHT :
124.64
WISWESSER LINE NOTATION :
G2S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
252 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32 mg/kg/4D-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases

MUTATION DATA

TEST SYSTEM :
Insect - Drosophila melanogaster
DOSE/DURATION :
5 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 13,19,1971

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301 + H311 + H331-H314-H350

[ Precautionary Statements ]:
P201-P261-P280-P301 + P310-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R10;R22;R36/37/38;R40

[ Safety Phrases ]:
S36/37/39-S26-S16-S45-S27

[ RIDADR ]:
1992

[ RTECS ]:
WQ3250000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(Ethylsulfanyl)ethanol
  • dichloroethane
  • Ethanethiol
  • 1-ethylsulfanyl-2-butoxy-ethane
  • Sodium ethanethiolate
  • ethene
  • ethyl thiohypochlorite
  • Thionyl chloride
  • 3,6-dithiaoctan-1-ol

DownStream

  • demeton-S-methyl
  • 1-Chloro-2-(ethylsulfinyl)ethane
  • Ethanol,2-(ethylsulfinyl)-
  • 1-ethenylsulfinylethane
  • Thiophene(SIV)
  • Ethanethiol
  • benzene
  • Ethane,1-chloro-2-(ethylsulfonyl)-
  • Ethene, (ethylthio)-(9Cl)
  • thiometon

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

An improved method for retrospective quantification of sulfur mustard exposure by detection of its albumin adduct using ultra-high pressure liquid chromatography-tandem mass spectrometry.

Anal. Bioanal. Chem 407 , 7037-46, (2015)

Sulfur mustard (HD) adduct to human serum albumin (ALB) at Cys-34 residue has become an important and long-term retrospective biomarker of HD exposure. Here, a novel, sensitive, and convenient approac...

Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.

Pediatr. Pulmonol. 50(2) , 118-26, (2015)

Inhalation of sulfur mustard (SM) and SM analog, 2-chloroethyl ethyl sulfide (CEES), cause fibrinous cast formation that occludes the conducting airways, similar to children with Fontan physiology-ind...

Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.

Toxicol. Appl. Pharmacol. 272(1) , 86-95, (2013)

Sulfur mustard (SM) inhalation causes airway injury, with enhanced vascular permeability, coagulation, and airway obstruction. The objective of this study was to determine whether recombinant tissue f...


More Articles

Related Compounds

  • 2-chloroethyl ethyl sulfide
  • 2-chloroethyl-ethyl-[(4-propan-2-ylphenyl)methyl]azanium chloride
  • 2-chloroethyl-ethyl-[2-(3-ethylphenoxy)ethyl]azanium,chloride
  • 2-chloroethyl-ethyl-[2-(2-methoxyphenoxy)ethyl]azanium,chloride
  • 2-chloroethyl-ethyl-[2-(2-propan-2-ylphenoxy)ethyl]azanium,chloride
  • 2-chloroethyl-ethyl-[2-(4-methylphenoxy)ethyl]azanium,chloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • (2S)-4-(6-chloro-2-methoxypyridin-3-yl)butan-2-ol
  • tert-butyl N-{2-chloro-5-[2-(methylamino)propan-2-yl]phenyl}carbamate
  • 2-methyl-4-[4-({2-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-3-yl}methyl)piperazin-1-yl]-6-(1H-pyrazol-1-yl)pyrimidine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-Chloro-3-(methylsulfamoyl)benzamide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide