2-Chloroethyl ethyl sulfide
2-Chloroethyl ethyl sulfide structure
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Common Name | 2-Chloroethyl ethyl sulfide | ||
|---|---|---|---|---|
| CAS Number | 693-07-2 | Molecular Weight | 124.63200 | |
| Density | 1.07 | Boiling Point | 156-157 °C | |
| Molecular Formula | C4H9ClS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 52 °C | |
| Symbol |
GHS02, GHS05, GHS06, GHS08 |
Signal Word | Danger | |
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An improved method for retrospective quantification of sulfur mustard exposure by detection of its albumin adduct using ultra-high pressure liquid chromatography-tandem mass spectrometry.
Anal. Bioanal. Chem 407 , 7037-46, (2015) Sulfur mustard (HD) adduct to human serum albumin (ALB) at Cys-34 residue has become an important and long-term retrospective biomarker of HD exposure. Here, a novel, sensitive, and convenient approach for retrospective quantification of HD concentration expo... |
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Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.
Pediatr. Pulmonol. 50(2) , 118-26, (2015) Inhalation of sulfur mustard (SM) and SM analog, 2-chloroethyl ethyl sulfide (CEES), cause fibrinous cast formation that occludes the conducting airways, similar to children with Fontan physiology-induced plastic bronchitis. These airway casts cause significa... |
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Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.
Toxicol. Appl. Pharmacol. 272(1) , 86-95, (2013) Sulfur mustard (SM) inhalation causes airway injury, with enhanced vascular permeability, coagulation, and airway obstruction. The objective of this study was to determine whether recombinant tissue factor pathway inhibitor (TFPI) could inhibit this pathogeni... |
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Facility monitoring of chemical warfare agent simulants in air using an automated, field-deployable, miniature mass spectrometer.
Rapid Commun. Mass Spectrom. 25(10) , 1437-44, (2011) Vapors of four chemical warfare agent (CWA) stimulants, 2-chloroethyl ethyl sulfide (CEES), diethyl malonate (DEM), dimethyl methylphosphonate (DMMP), and methyl salicylate (MeS), were detected, identified, and quantitated using a fully automated, field-deplo... |
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Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation.
Am. J. Respir. Cell. Mol. Biol. 51(4) , 559-67, (2014) Acute lung injury in response to mustard gas (sulfur mustard [SM]) inhalation results in formation of fibrin casts, which obstruct the airway. The objective of this study was to identify fibrinolytic pathways that could be contributing to the persistence of a... |
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Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.
Chem. Biol. Interact. 206(3) , 523-8, (2013) Sulfur mustard (SM) is an old chemical warfare agent causing blisters (vesicant). Skin toxicity is thought to be partly caused by SM induced DNA damage. SM and the hemi mustard 2-chloroethyl ethyl sulfide (CEES) are bi- and monofunctional DNA alkylating agent... |
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Antioxidant liposomes protect against CEES-induced lung injury by decreasing SAF-1/MAZ-mediated inflammation in the guinea pig lung.
J. Biochem. Mol. Toxicol. 24(3) , 187-94, (2010) We reported earlier in a guinea pig model that exposure of 2-chloroethyl ethyl sulfide (CEES), a mustard gas analog, causes lung injury associated with the activation of tumor necrosis factor alpha (TNF-alpha), mitogen activated protein kinases (MAPK) signali... |
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Induction of neuronal damage in guinea pig brain by intratracheal infusion of 2-chloroethyl ethyl sulfide, a mustard gas analog.
J. Biochem. Mol. Toxicol. 26(1) , 23-30, (2012) Intratracheal infusion of 2-chloroethyl ethyl sulfide (CEES), a mustard gas analog and a chemical warfare agent is known to cause massive damage to lung. The purpose of this study was to determine whether intratracheal CEES infusion causes neuronal damage. Hi... |
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Sodium pyruvate modulates cell death pathways in HaCaT keratinocytes exposed to half-mustard gas.
Int. J. Toxicol. 30(2) , 197-206, (2011) 2-Chloroethyl ethyl sulfide (CEES) or half-mustard gas, a sulfur mustard (HD) analog, is a genotoxic agent that causes oxidative stress and induces both apoptotic and necrotic cell death. Sodium pyruvate induced a necrosis-to-apoptosis shift in HaCaT cells ex... |
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Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.
Toxicol. Appl. Pharmacol. 261(1) , 22-30, (2012) Pulmonary toxicity induced by sulfur mustard and related vesicants is associated with oxidative stress. In the present studies we analyzed the role of reactive nitrogen species (RNS) generated via inducible nitric oxide synthase (iNOS) in lung injury and infl... |