()-Eseroline fumarate salt

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Names

[ CAS No. ]:
70310-73-5

[ Name ]:
()-Eseroline fumarate salt

[Synonym ]:
(-)-Eseroline fumarate salt
(u2212)-Eseroline fumarate salt
E100_FLUKA

Chemical & Physical Properties

[ Molecular Formula ]:
C17H22N2O5

[ Molecular Weight ]:
334.36700

[ Exact Mass ]:
334.15300

[ PSA ]:
101.31000

[ LogP ]:
1.47600

[ Appearance of Characters ]:
white

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
0.1 M HCl: soluble (Solutions should be freshly prepared.)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Reversible inhibition of acetylcholinesterase by eseroline, an opioid agonist structurally related to physostigmine (eserine) and morphine.

Biochem. Pharmacol. 31 , 1233, (1982)

The action of eseroline--(3aS,8aR)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indo l-5-ol--salicylate was tested on preparations of ChE from different sources and on the longitudinal muscle...

Direct evidence that eseroline possesses morphine-like effects.

Eur. J. Pharmacol. 83 , 232, (1982)

The opiate-like effects of eseroline, a physostigmine derivative, were studied in different tests. The antinociceptive effect of eseroline given s.c. and intracerebrally could be detected in the rat h...

Eseroline, a metabolite of physostigmine, induces neuronal cell death.

Toxicol. Appl. Pharmacol. 106 , 28, (1990)

The toxic effects of physostigmine, an anticholinesterase drug, and its metabolite eseroline were investigated in three neuronal cell culture systems, mouse neuroblastoma N1E-115, rat glioma C6, and n...


More Articles

Related Compounds

  • (-)-eseroline fumarate
  • Siramesine fumarate salt
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  • 4-(2-cyano-9-thioxanthenylidene)-1-methylpiperidine fumarate salt