Bay K-8644

Suppliers

Names

[ Name ]:
Bay K-8644

[Synonym ]:
(1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)-phenyl]-3-pyridine carboxylic acid methyl ester
rac-Aziridin-2-carbonitril
methyl-1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethylphenyl)-pyridine-3-carboxylate
(+/-)-Aziridin-2-carbonitril
cyano-2 aziridine
(-)-2,6-dimethyl-3-carbomethoxy-5-nitro-4-(2-trifluoromethylphenyl)-1,4-dihydropyridine
2-aziridinecarbonitrile
MFCD00036697
2-cyano-2-aziridine
(.+/-.)-Bay K 8644
nitrile of aziridine-2-carboxylic acid
Bay K-8644

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
404.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₅F₃N₂O₄

[ Molecular Weight ]:
356.29700

[ Flash Point ]:
198.3ºC

[ Exact Mass ]:
356.09800

[ PSA ]:
84.15000

[ LogP ]:
4.19940

[ Index of Refraction ]:
1.545

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Nitroacetone
2-(Trifluoromethyl)benzaldehyde
Methyl (Z)-3-aminocrotonate
methyl 2-(2-trifluoromethylphenylmethylene)acetoacetate

DownStream

Articles

Metformin as adjunct antituberculosis therapy.

Sci. Transl. Med. 6(263) , 263ra159, (2014)

The global burden of tuberculosis (TB) morbidity and mortality remains immense. A potential new approach to TB therapy is to augment protective host immune responses. We report that the antidiabetic d...

Magnesium sulfate provides neuroprotection in lipopolysaccharide-activated primary microglia by inhibiting NF-κB pathway.

J. Surg. Res. 184(2) , 944-50, (2013)

Magnesium sulfate has been used as an anticonvulsant in severe preeclamptic or eclamptic women prior to surgical trauma, but its effects on neuroinflammation is not well defined. In the present study,...

Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system.

J. Physiol. 586(7) , 1963-75, (2008)

The regulation of neuromediator expression by neuronal activity in the enteric nervous system (ENS) is currently unknown. Using primary cultures of ENS derived from rat embryonic intestine, we have ch...

Bay K-8644
(S)-(-)-Bay K 8644
(+/-)-BAY K 8644
(R)-(+)-Bay K 8644
bay-k 8643
Fuzlocillin
1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]cyclobutane-1-carboxylic acid
4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2,2-dimethylbutanoic acid
1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylpropanamido]cyclopentane-1-carboxylic acid
3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylpentanamido]-2-methylpropanoic acid
(2S)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,4-dimethylpentanamido]propanoic acid
(3S)-1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-ynoyl]piperidine-3-carboxylic acid
1-(2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]sulfanyl}acetyl)-4-hydroxypiperidine-4-carboxylic acid
4-(2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]sulfanyl}acetamido)-3-methylbutanoic acid
benzyl N-[1-(oxan-4-yl)prop-2-en-1-yl]carbamate
2-(2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]sulfanyl}acetamido)-2-methylbutanoic acid

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