Bay K-8644
Bay K-8644 structure
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Common Name | Bay K-8644 | ||
|---|---|---|---|---|
| CAS Number | 71145-03-4 | Molecular Weight | 356.29700 | |
| Density | 1.37g/cm3 | Boiling Point | 404.3ºC at 760 mmHg | |
| Molecular Formula | C16H15F3N2O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 198.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Metformin as adjunct antituberculosis therapy.
Sci. Transl. Med. 6(263) , 263ra159, (2014) The global burden of tuberculosis (TB) morbidity and mortality remains immense. A potential new approach to TB therapy is to augment protective host immune responses. We report that the antidiabetic drug metformin (MET) reduces the intracellular growth of Myc... |
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Magnesium sulfate provides neuroprotection in lipopolysaccharide-activated primary microglia by inhibiting NF-κB pathway.
J. Surg. Res. 184(2) , 944-50, (2013) Magnesium sulfate has been used as an anticonvulsant in severe preeclamptic or eclamptic women prior to surgical trauma, but its effects on neuroinflammation is not well defined. In the present study, we investigated the neuroprotective effects of magnesium s... |
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Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system.
J. Physiol. 586(7) , 1963-75, (2008) The regulation of neuromediator expression by neuronal activity in the enteric nervous system (ENS) is currently unknown. Using primary cultures of ENS derived from rat embryonic intestine, we have characterized the regulation of tyrosine hydroxylase (TH), a ... |
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A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.
Genes Dev. 24 , 183-94, (2010) Eukaryotes have numerous checkpoint pathways to protect genome fidelity during normal cell division and in response to DNA damage. Through a screen for G2/M checkpoint regulators in zebrafish, we identified ticrr (for TopBP1-interacting, checkpoint, and repli... |