Metandienone
Suppliers
Names
[ CAS No. ]:
72-63-9
[ Name ]:
Metandienone
[Synonym ]:
1-Dehydro-17a-methyltestosterone
Androsta-1,4-dien-3-one, 17β-hydroxy-17α-methyl-
Androsta-1,4-dien-3-one, 17β-hydroxy-17-methyl-
1-Dehydro-17α-methyltestosterone
Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17β)-
EINECS 200-787-2
(17β)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
17a-Methyl-17b-hydroxyandrosta-1,4-dien-3-one
17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one (9CI)
Metandienone
(17b)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
Nabolin
17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one
Methandienone
Methandrostenolone
MFCD00003650
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
436.5±45.0 °C at 760 mmHg
[ Melting Point ]:
165-166 °C
[ Molecular Formula ]:
C20H28O2
[ Molecular Weight ]:
300.435
[ Flash Point ]:
186.2±21.3 °C
[ Exact Mass ]:
300.208923
[ PSA ]:
37.30000
[ LogP ]:
4.04
[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C
[ Index of Refraction ]:
1.572
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8000000
- CHEMICAL NAME :
- Androsta-1,4-dien-3-one, 17-beta-hydroxy-17-alpha-methyl-
- CAS REGISTRY NUMBER :
- 72-63-9
- LAST UPDATED :
- 199504
- WISWESSER LINE NOTATION :
- L E5 B666 OV AHTTT&J A1 E1 FQ F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 425 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 561 mg/kg/7Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 13 mg/kg
- SEX/DURATION :
- male 60 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 200 mg/kg
- SEX/DURATION :
- female 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 200 mg/kg
- SEX/DURATION :
- male 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 7 mg/kg
- SEX/DURATION :
- female 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - other measures of fertility
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg/10D (Intermittent)
- REFERENCE :
- VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 38(4),63,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5642 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 157 (estimated) No. of Female Employees: 72 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H315-H360FD
[ Supplemental HS ]:
May form explosive peroxides.
[ Precautionary Statements ]:
P201-P210-P280-P308 + P313-P370 + P378-P403 + P235
[ Hazard Codes ]:
F,T
[ Risk Phrases ]:
60-61-11-19-38
[ Safety Phrases ]:
53-45
[ RIDADR ]:
3249
[ WGK Germany ]:
3
[ RTECS ]:
BV8000000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2942000000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2942000000
Articles
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