N-Biotinyl-6-aminohexanoic acid

Names

[ CAS No. ]:
72040-64-3

[ Name ]:
N-Biotinyl-6-aminohexanoic acid

[Synonym ]:
6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoic acid

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
721.3ºC at 760 mmHg

[ Melting Point ]:
220-230ºC (dec.)

[ Molecular Formula ]:
C₁₆H₂₇N₃O₄S

[ Molecular Weight ]:
357.46800

[ Flash Point ]:
390ºC

[ Exact Mass ]:
357.17200

[ PSA ]:
132.83000

[ LogP ]:
2.52190

[ Index of Refraction ]:
1.532

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F: Flammable;

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

D-Biotin
6-Aminocaproic acid
Biotin NHS
Biotin-PFP ester
Methyl 6-aminohexanoate hydrochloride

DownStream

Biotin-C5-amino-C5-amino
Biotin-C5-NHS Ester

Articles

In vivo labeling of Escherichia coli cell envelope proteins with N-hydroxysuccinimide esters of biotin. Bradburne JA, Godfrey P, et al.

Appl. Environ. Microbiol. 59 , 663-668, (2993)

(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.

Mol. Pharmacol. 68 , 1623-35, (2005)

The CB1 cannabinoid receptor has been shown to play important physiological roles in the central nervous system, as well as peripherally, and is a target for development of therapeutic medications. To...

microAg particle-based molecular sensing/recognition via surface-enhanced Raman spectroscopy.

Biosens. Bioelectron. 22 , 1000-1005, (2007)

In this study, we demonstrate that powders of commercially available 2-microm-sized Ag (microAg) can be used as a core material for constructing molecular sensing/recognition units operating via surfa...

N -methoxycarbonyl-6-aminohexanoic acid
N-Cbz-6-aminohexanoic acid pentafluorophenol ester
N-naproxyl-6-aminohexanoic acid
N-Benzyloxycarbonyl-6-aminohexanoic acid
N-BIOTINYL-6-AMINO-2-NAPHTHOIC ACID
Methyl 6-(Boc-amino)hexanoate
N-((3-(furan-3-yl)pyrazin-2-yl)methyl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
5-(4-benzyl-1-piperazinyl)-4-bromo-2-phenyl-3(2H)-pyridazinone
2-(4-fluorophenyl)-N-((3-(furan-3-yl)pyrazin-2-yl)methyl)acetamide
2-phenyl-1,4-benzoxazepine-3,5(2H,4H)-dione
N-((3-(furan-3-yl)pyrazin-2-yl)methyl)-4-propylbenzamide
N-{4-[(4-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}piperidin-1-yl)sulfonyl]phenyl}acetamide
N-((3-(furan-3-yl)pyrazin-2-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide
4-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]-2-methyl-1,4-benzoxazepine-3,5(2H,4H)-dione
2-(2-chlorophenyl)-N-((3-(furan-3-yl)pyrazin-2-yl)methyl)acetamide
4-[3-(4-Chlorophenyl)-4-methylpentyl]morpholine

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