N-Biotinyl-6-aminohexanoic acid

Names

[ CAS No. ]:
72040-64-3

[ Name ]:
N-Biotinyl-6-aminohexanoic acid

[Synonym ]:
6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoic acid

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
721.3ºC at 760 mmHg

[ Melting Point ]:
220-230ºC (dec.)

[ Molecular Formula ]:
C₁₆H₂₇N₃O₄S

[ Molecular Weight ]:
357.46800

[ Flash Point ]:
390ºC

[ Exact Mass ]:
357.17200

[ PSA ]:
132.83000

[ LogP ]:
2.52190

[ Index of Refraction ]:
1.532

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F: Flammable;

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

D-Biotin
6-Aminocaproic acid
Biotin NHS
Biotin-PFP ester
Methyl 6-aminohexanoate hydrochloride

DownStream

Biotin-C5-amino-C5-amino
Biotin-C5-NHS Ester

Articles

In vivo labeling of Escherichia coli cell envelope proteins with N-hydroxysuccinimide esters of biotin. Bradburne JA, Godfrey P, et al.

Appl. Environ. Microbiol. 59 , 663-668, (2993)

(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.

Mol. Pharmacol. 68 , 1623-35, (2005)

The CB1 cannabinoid receptor has been shown to play important physiological roles in the central nervous system, as well as peripherally, and is a target for development of therapeutic medications. To...

microAg particle-based molecular sensing/recognition via surface-enhanced Raman spectroscopy.

Biosens. Bioelectron. 22 , 1000-1005, (2007)

In this study, we demonstrate that powders of commercially available 2-microm-sized Ag (microAg) can be used as a core material for constructing molecular sensing/recognition units operating via surfa...

N -methoxycarbonyl-6-aminohexanoic acid
N-Cbz-6-aminohexanoic acid pentafluorophenol ester
N-naproxyl-6-aminohexanoic acid
N-Benzyloxycarbonyl-6-aminohexanoic acid
N-BIOTINYL-6-AMINO-2-NAPHTHOIC ACID
Methyl 6-(Boc-amino)hexanoate
5-[4-[5-fluoro-6-(4-methoxyphenyl)pyrimidin-4-yl]piperazine-1-carbonyl]-3-methyl-5H-pyrimidine-2,4-dione
6-(Difluoromethyl)-2-[4-(6-fluoroquinazolin-4-yl)piperazin-1-yl]-1,3-diazinan-4-one
7-methoxy-N-[[3-(2-oxo-3H-pyridin-3-yl)-1,2,4-oxadiazol-5-yl]methyl]-1-benzofuran-2-carboxamide
3-butyl-1-ethyl-4aH-thieno[3,2-d]pyrimidin-1-ium-2,4-dione
6-Cyclopropyl-2-[4-([1,3]thiazolo[4,5-c]pyridin-2-yl)piperazin-1-yl]-1,3-diazinan-4-one
2-[4-(5-Chloro-4-methyl-1,3-benzothiazol-2-yl)piperazin-1-yl]-6-(difluoromethyl)-1,3-diazinan-4-one
N-[2-(2,4-dioxo-4aH-thieno[3,2-d]pyrimidin-3-yl)ethyl]-2-phenyltriazole-4-carboxamide
4,6-dimethyl-N-(2-oxobenzimidazol-5-yl)pyrimidine-2-carboxamide
N-[2-(2,4-dioxo-4a,7a-dihydro-1H-thieno[3,2-d]pyrimidin-3-yl)ethyl]-4-phenyloxane-4-carboxamide
5-Fluoro-6-methyl-2-[5-[2-(1-methylindol-3-yl)acetyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-1,3-diazinan-4-one

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