Chloromethyl 4-chlorophenyl sulfide

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Names

[ Name ]:
Chloromethyl 4-chlorophenyl sulfide

[Synonym ]:
Chloromethyl 4-chlorophenyl sulphide
Chloromethyl 4-chlorophenyl sulfide
Sulfide,chloromethyl p-chlorophenyl
MFCD00000922
Thiophenol,p-chloro-S-chloromethyl
BENZENE, 1-CHLORO-4-(CHLOROMETHYLTHIO)-
EINECS 230-578-1
1-Chloro-4-[(chloromethyl)sulfanyl]benzene
chloromethyl p-chlorophenyl sulfide
4-chlorophenylthio-methyl chloride
Chlormethyl-(4-chlor-phenyl)-sulfid
p-Chloro-S-chloromethylbenzenethiol
Benzene, 1-chloro-4-[(chloromethyl)thio]-
Sulfide, chloromethyl p-chlorophenyl
1-Chloro-4-(chloromethylthio)benzene
p-chlorophenyl chloromethyl sulfide
p-Chlorfenyl-chlormethylsulfid [Czech]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
261.9±0.0 °C at 760 mmHg

[ Melting Point ]:
21.5°C

[ Molecular Formula ]:
C₇H₆Cl₂S

[ Molecular Weight ]:
193.094

[ Flash Point ]:
103.2±20.3 °C

[ Exact Mass ]:
191.956726

[ PSA ]:
25.30000

[ LogP ]:
3.67

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.601

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ0200000

CHEMICAL NAME :: Benzene, 1-chloro-4-(chloromethylthio)-

CAS REGISTRY NUMBER :: 7205-90-5

BEILSTEIN REFERENCE NO. :: 2043507

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H6-Cl2-S

MOLECULAR WEIGHT :: 193.09

WISWESSER LINE NOTATION :: G1SR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,996,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,996,1986

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26;S27;S28;S45;S36/S37/S39

[ RIDADR ]:
UN 3265

[ WGK Germany ]:
3

[ RTECS ]:
CZ0200000

[ Packaging Group ]:
III

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Chlorophenyl methyl sulfide
Formaldehyde
4-Chlorothiophenol
Bromochloromethane
(4-chlorophenyl)sulfanylmethyl-trimethylsilane
1-chloro-3-methylsulfinylbenzene
4-Chlorobenzenesulfonyl chloride
(4-chloro-phenylsulfanyl)-methanesulfonic acid

DownStream

Benzene,1-chloro-4-[[(1R,2S)-2-phenylcyclopropyl]sulfonyl]-, rel-
Dagadip
Ethyl 3-(4-chloro-3,5-dimethylphenoxy)propanoate
1-chloro-4-[(4-chlorophenyl)sulfanylmethylsulfanyl]benzene
1-chloro-4-(diethoxyphosphorylsulfanylmethylsulfanyl)benzene
1-chloro-4-(fluoromethylsulfinyl)benzene
Benzene,1-chloro-4-[[(4-nitrophenoxy)methyl]sulfonyl]-
2-[(4-chlorophenyl)sulfanylmethylsulfanyl]-1-methylpyridin-1-ium,chloride
(4-chlorophenyl) thiohypochlorite
Benzene,1-chloro-4-[(chloromethyl)sulfonyl]-

Articles

Nucleophilic Participation in the Solvolyses of (Arylthio)methyl Chlorides and Derivatives: Application of Simple and Extended Forms of the Grunwald-Winstein Equations.

Curr. Org. Chem. 16(12) , 1502-1511, (2012)

The specific rates of solvolysis of chloromethyl phenyl sulfide [(phenylthio)methyl chloride] and its p-chloro-derivative have been determined at 0.0 _C in a wide range of hydroxylic solvents, includi...

Synthesis of α-Haloalkyl Esters from α-Arylthioalkyl Esters. Benneche T, et al.

Acta Chem. Scand. 43 , 74-77, (1988)

A new approach to the synthesis of 2-aminoimidazo [1, 2-a]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines. Vega JA, et al.

Tetrahedron 55(8) , 2317-2326, (1999)