Miglitol

Suppliers

Names

[ Name ]:
Miglitol

[Synonym ]:
BAY m 1099
Miglitol
(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidin-3,4,5-triol
Diastabol
(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol
EINECS 276-661-6
MFCD00867240
GLYSET
Plumarol
BAY-m-1099
Seibule
(2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
N-(2-Hydroxyethyl)moranoline
3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R,3R,4R,5S)-
BAY 1099
(2R,3R,4R,5S)-1-(2-hydroxyéthyl)-2-(hydroxyméthyl)pipéridine-3,4,5-triol

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
453.7±45.0 °C at 760 mmHg

[ Melting Point ]:
114ºC

[ Molecular Formula ]:
C₈H₁₇NO₅

[ Molecular Weight ]:
207.224

[ Flash Point ]:
284.3±27.4 °C

[ Exact Mass ]:
207.110672

[ PSA ]:
104.39000

[ LogP ]:
-1.40

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.598

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
Soluble

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-(2-benzyloxyethyl)-1-deoxynojirimycin
N-(2-hydroxy-ethyl)-2,3,4,6-tetra-O-benzyl-1-deoxynojirimycin
1-Deoxynojirimycin
2-(Benzyloxy)acetaldehyde
((2R,3R,4R,5S)-3,4,5-tris(benzyloxy)-1-(2-(benzyloxy)ethyl)piperidin-2-yl)methanol
2-Bromoethanol
(2S,3R,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxyhexyl pivalate
(2S,3R,4S,5S,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol
((2S,3R,4R,5S)-3,4,5-tris(benzyloxy)-1-(2-(benzyloxy)ethyl)piperidin-2-yl)methanol

DownStream

Articles

Specificity of Processing α-glucosidase I is guided by the substrate conformation: crystallographic and in silico studies.

J. Biol. Chem. 288(19) , 13563-74, (2013)

The enzyme “GluI” is key to the synthesis of critical glycoproteins in the cell.We have determined the structure of GluI, and modeled binding with its unique sugar substrate.The specificity of this in...

Study of the inhibition of two human maltase-glucoamylases catalytic domains by different α-glucosidase inhibitors.

Carbohydr. Res. 346(17) , 2688-92, (2011)

In humans, both the N-terminal catalytic domain (NtMGAM) and the C-terminal catalytic domain (CtMGAM) of small intestinal maltase glucoamylase (MGAM) are α-glycosidases that catalyze the hydrolysis of...

Beneficial effects of vildagliptin combined with miglitol on glucose tolerance and islet morphology in diet-controlleddb/dbmice

Biochem. Biophys. Res. Commun. 440(4) , 570-5, (2013)

• Beneficial effects of combination therapy with vildagliptin plus miglitol on glucose tolerance of db/db mice were evaluated. • Postprandial glucose- and incretin response was normalized by the combi...

Miglitol-d4
Miglitol-d4 Hydrochloride
Miglitol-d4 hydrochloride
4-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-2-hydroxybutanoic acid
(2R)-2-phenyl-2-{[(1rs,3rs)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}acetic acid
4-ethyl-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutanecarbonyl]piperidine-2-carboxylic acid
3-(dimethylamino)-2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]propanoic acid
2-[3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-(prop-2-en-1-yl)propanamido]acetic acid
4-[3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]morpholine-2-carboxylic acid
3-[({bicyclo[3.1.0]hexan-2-yl}methyl)carbamoyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
(1R,5S)-3-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropanecarbonyl}-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
3-(3-Fluoropyridin-4-yl)thiophene-2-carbaldehyde
3-Fluoro-4-(3-fluoro-4-nitrophenyl)pyridine

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