ici-118,551

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Names

[ CAS No. ]:
72795-19-8

[ Name ]:
ici-118,551

[Synonym ]:
ICI 118,551 HYDROCHLORIDE
MFCD00153812
Ici 111,581
ICI-118-551 HYDROCHLORIDE HIGHLY SELECTI VE B2 A

Chemical & Physical Properties

[ Boiling Point ]:
439.3ºC at 760 mmHg

[ Molecular Formula ]:
C17H28ClNO2

[ Molecular Weight ]:
313.86300

[ Flash Point ]:
219.5ºC

[ Exact Mass ]:
313.18100

[ PSA ]:
41.49000

[ LogP ]:
3.80280

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium.

Mol. Pharmacol. 35 , 295-303, (1989)

Prenalterol (beta 1-agonist), denopamine (beta 1-agonist), and zinterol (beta 2-agonist) were partial agonists of adenylate cyclase (AC) stimulation in human ventricular myocardium obtained from nonfa...

Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.

J. Pharmacol. Exp. Ther. 249 , 911-920, (1989)

The localization and number of beta adrenergic receptors were directly compared in the brains of rats and guinea pigs. The time course of association and saturability of [125I]cyanopindolol (CYP) bind...

The pharmacology of a beta 2-selective adrenoceptor antagonist (ICI 118,551).

J. Cardiovasc. Pharmacol. 5 , 430, (1983)

While specific antagonists of the beta 1-adrenoceptor, such as atenolol and betaxolol, are widely available, a potent specific antagonist selective for the beta 2-adrenoceptor has yet to be described....


More Articles

Related Compounds

  • ICI-118551
  • rel-ICI 118551-d7 hydrochloride
  • threo-ICI 118551 Hydrochloride
  • 2-(3,4-dichlorophenyl)-N-[1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-ylethyl]-N-methylacetamide,hydrochloride
  • ICI 45849 hydrochloride
  • ICI 162,846