ici-118,551
ici-118,551 structure
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Common Name | ici-118,551 | ||
|---|---|---|---|---|
| CAS Number | 72795-19-8 | Molecular Weight | 313.86300 | |
| Density | N/A | Boiling Point | 439.3ºC at 760 mmHg | |
| Molecular Formula | C17H28ClNO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 219.5ºC | |
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Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium.
Mol. Pharmacol. 35 , 295-303, (1989) Prenalterol (beta 1-agonist), denopamine (beta 1-agonist), and zinterol (beta 2-agonist) were partial agonists of adenylate cyclase (AC) stimulation in human ventricular myocardium obtained from nonfailing chambers whose beta 1/beta 2 receptor subtype ratio w... |
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Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.
J. Pharmacol. Exp. Ther. 249 , 911-920, (1989) The localization and number of beta adrenergic receptors were directly compared in the brains of rats and guinea pigs. The time course of association and saturability of [125I]cyanopindolol (CYP) binding to slide-mounted tissue sections was similar in rats (K... |
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The pharmacology of a beta 2-selective adrenoceptor antagonist (ICI 118,551).
J. Cardiovasc. Pharmacol. 5 , 430, (1983) While specific antagonists of the beta 1-adrenoceptor, such as atenolol and betaxolol, are widely available, a potent specific antagonist selective for the beta 2-adrenoceptor has yet to be described. Previously described beta 2-selective antagonists such as ... |
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Implications of a vasodilatory human monoclonal autoantibody in postural hypotension.
J. Biol. Chem. 288(42) , 30734-41, (2013) Functional autoantibodies to the autonomic receptors are increasingly recognized in the pathophysiology of cardiovascular diseases. To date, no human activating monoclonal autoantibodies to these receptors have been available. In this study, we describe for t... |