2,4,6-Tri-tert-butylphenol
Suppliers
Names
[ CAS No. ]:
732-26-3
[ Name ]:
2,4,6-Tri-tert-butylphenol
[Synonym ]:
MFCD00008821
2,4,6-tri-tert-butyl phenol
2,4,6-Tri-tert-butylphenol
2,4,6-tritert-butylphenol
2,4,6-Tri-tert-butylbenzolol
EINECS 211-989-5
2,4,6-Tris(2-methyl-2-propanyl)phenol
2,4,6-TRI(TERT-BUTYL)PHENOL
Phenol, 2,4,6-tris(1,1-dimethylethyl)-
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
278.0±0.0 °C at 760 mmHg
[ Melting Point ]:
125-130 °C(lit.)
[ Molecular Formula ]:
C18H30O
[ Molecular Weight ]:
262.430
[ Flash Point ]:
129.3±8.4 °C
[ Exact Mass ]:
262.229675
[ PSA ]:
20.23000
[ LogP ]:
6.55
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.490
[ Storage condition ]:
-20°C
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SN3570000
- CHEMICAL NAME :
- Phenol, 2,4,6-tris(1,1-dimethylethyl)-
- CAS REGISTRY NUMBER :
- 732-26-3
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C18-H30-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1670 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Liver - other changes
- REFERENCE :
- SRTCAC Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. (Tohoku University, Research Institute for Tuberculosis and Cancer, 4-1 Seiryo-machi, Sendai, Japan) V.1- 1949- Volume(issue)/page/year: 36(1-4),10,1989 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8580 mg/kg/10D-C
- TOXIC EFFECTS :
- Blood - hemorrhage Related to Chronic Data - death
- REFERENCE :
- JONUAI Journal of Nutrition. (Subscription Dept., 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1928- Volume(issue)/page/year: 109,453,1979
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10914 mg/kg/3W-C
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Blood - hemorrhage Related to Chronic Data - death
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 46,935,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4377 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 211 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4377 No. of Facilities: 279 (estimated) No. of Industries: 4 No. of Occupations: 13 No. of Employees: 12085 (estimated) No. of Female Employees: 239 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H400
[ Precautionary Statements ]:
P273-P301 + P312 + P330-P391
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36/37/39-S45-S60-S61-S24/25
[ RIDADR ]:
UN 2430 8/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SN3570000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Chemosphere 88(1) , 62-8, (2012)
The application of in-tissue passive sampling to quantify chemical kinetics in fish bioconcentration experiments was investigated. A passive sampler consisting of an acupuncture needle covered with a ...
In Vitr. Mol. Toxicol. 14(1) , 53-63, (2001)
2,4,6-Tri-tert-butylphenol (TBP)-related compounds are used for stabilizing plastics by making them resistant to oxidation. However, the cytotoxic activity of these compounds has not yet been establis...
Phys. Chem. Chem. Phys. 13(28) , 12745-54, (2011)
The phenol, α-tocopherol, can be electrochemically oxidised in a -2e(-)/-H(+) process to form a diamagnetic cation that is long-lived in dry organic solvents such as acetonitrile and dichloromethane, ...