17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one

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Names

[ CAS No. ]:
73671-86-0

[ Name ]:
17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one

Chemical & Physical Properties

[ Density]:
1.051g/cm3

[ Boiling Point ]:
528.3ºC at 760 mmHg

[ Molecular Formula ]:
C24H40N2O2

[ Molecular Weight ]:
388.59

[ Flash Point ]:
209.8ºC

[ Exact Mass ]:
388.30900

[ PSA ]:
40.62000

[ LogP ]:
4.27230

[ Index of Refraction ]:
1.519

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CL5200000
CHEMICAL NAME :
5-alpha-4-Azaandrostane-17-beta-carboxamide, N,N-diethyl-4-methyl-3-oxo-
CAS REGISTRY NUMBER :
73671-86-0
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C24-H40-N2-O2
MOLECULAR WEIGHT :
388.66

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
2100 mg/kg
SEX/DURATION :
male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,67,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
700 mg/kg
SEX/DURATION :
male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,67,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
135 mg/kg
SEX/DURATION :
female 13-21 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,67,1982

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-(2-Fluorophenyl)-4-[1-[2-hydroxy-3-(3-methylphenoxy)propyl]benzimidazol-2-yl]pyrrolidin-2-one
  • 4-Butoxy-3-fluorobenzonitrile
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 6-(((3-(4-ethylphenyl)-1,2,4-oxadiazol-5-yl)methyl)thio)-7-(2-methoxyethyl)-[1,3]dioxolo[4,5-g]quinazolin-8(7H)-one
  • 3-(4-Chlorophenyl)-1-benzofuran-5-ol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide