SIB-1893

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Names

[ CAS No. ]:
7370-21-0

[ Name ]:
SIB-1893

[Synonym ]:
6-METHYL-2-(NAPHTHALEN-2-YL)BENZOIC ACID
2-Methyl-6-(2-naphthyl)-benzoesaeure
(E)-2-methyl-6-styrylpyridine
2-Methyl-6-(2-phenylethenyl)pyridine
(E)-2-methyl-6-styrypyridine
(E)-6-methyl-2-styryl-pyridine
2-methyl-6-[(E)-2-phenylethenyl]pyridine

Chemical & Physical Properties

[ Molecular Formula ]:
C14H13N

[ Molecular Weight ]:
195.26000

[ Exact Mass ]:
195.10500

[ PSA ]:
12.89000

[ LogP ]:
3.56040

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP.

Br. J. Pharmacol. 138(6) , 1026-30, (2003)

We have identified 2-methyl-6-(2-phenylethenyl)pyridine (SIB-1893) and 2-methyl-6-phenylethynyl pyridine hydrochloride (MPEP) as positive allosteric modulators for the hmGluR4. SIB-1893 and MPEP enhan...

SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5.

J. Pharmacol. Exp. Ther. 290 , 170-181, (1999)

Cell lines expressing the human metabotropic glutamate receptor subtype 5a (hmGluR5a) and hmGluR1b were used as targets in an automated high-throughput screening (HTS) system that measures changes in ...


More Articles

Related Compounds

  • SIB 1893
  • SIB 1508Y maleate
  • SIB 1508Y
  • SIB-1553A
  • SIB 1757
  • CYM 50308
  • 1-(4-((Isopropyl(trifluoromethyl)amino)methyl)phenyl)ethanone
  • Methyl 2-(benzyloxy)-5-chloro-4-methylbenzoate
  • Methyl 3-{[(3,6-dichloropyridin-2-yl)formamido]methyl}-4-fluorobenzoate
  • 1-oxo-N~4~-(2-pyridylmethyl)-2-(3,4,5-trifluorophenyl)-1,2-dihydro-4-isoquinolinecarboxamide
  • N-{4-[5-(methoxymethyl)-1H-1,2,4-triazol-3-yl]phenyl}-1-methyl-1H-indole-2-carboxamide
  • 5-Chloro-2,3-dimethylbenzoic acid
  • 2,6-dichloro-N-(2-oxo-1-phenylazetidin-3-yl)benzene-1-sulfonamide
  • 4-chloro-N-methyl-N-{4-[4-(methylamino)phenyl]cyclohexyl}benzamide
  • tert-Butyl (1R,5S,7s)-7-(((benzyloxy)carbonyl)amino)-9-oxo-3-azabicyclo[3.3.1]nonane-3-carboxylate
  • 3-cyano-N-(1-cyano-1-methylbutyl)benzamide