SIB-1893

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Names

[ CAS No. ]:
7370-21-0

[ Name ]:
SIB-1893

[Synonym ]:
6-METHYL-2-(NAPHTHALEN-2-YL)BENZOIC ACID
2-Methyl-6-(2-naphthyl)-benzoesaeure
(E)-2-methyl-6-styrylpyridine
2-Methyl-6-(2-phenylethenyl)pyridine
(E)-2-methyl-6-styrypyridine
(E)-6-methyl-2-styryl-pyridine
2-methyl-6-[(E)-2-phenylethenyl]pyridine

Chemical & Physical Properties

[ Molecular Formula ]:
C14H13N

[ Molecular Weight ]:
195.26000

[ Exact Mass ]:
195.10500

[ PSA ]:
12.89000

[ LogP ]:
3.56040

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP.

Br. J. Pharmacol. 138(6) , 1026-30, (2003)

We have identified 2-methyl-6-(2-phenylethenyl)pyridine (SIB-1893) and 2-methyl-6-phenylethynyl pyridine hydrochloride (MPEP) as positive allosteric modulators for the hmGluR4. SIB-1893 and MPEP enhan...

SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5.

J. Pharmacol. Exp. Ther. 290 , 170-181, (1999)

Cell lines expressing the human metabotropic glutamate receptor subtype 5a (hmGluR5a) and hmGluR1b were used as targets in an automated high-throughput screening (HTS) system that measures changes in ...


More Articles

Related Compounds

  • SIB 1893
  • SIB 1508Y maleate
  • SIB 1508Y
  • SIB-1553A
  • SIB 1757
  • CYM 50308
  • N-(2-cyclopropylethyl)-6-(4-{6-[(2-cyclopropylethyl)carbamoyl]pyridazin-3-yl}piperazin-1-yl)pyridazine-3-carboxamide
  • 5-hydroxy-1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde
  • (4-(Tert-butyl)phenyl)(4-(((4,5-dihydrothiazol-2-yl)thio)methyl)piperidin-1-yl)methanone
  • Benzo[d][1,3]dioxol-5-yl(4-(((4,5-dihydrothiazol-2-yl)thio)methyl)piperidin-1-yl)methanone
  • 2-(3,4-Dipropoxybenzenesulfonamido)benzoic acid
  • (2-Chloro-6-fluorophenyl)(4-(((4,5-dihydrothiazol-2-yl)thio)methyl)piperidin-1-yl)methanone
  • 2-Thiophenesulfonamide,5-(2-thiazolylsulfonyl)-
  • 2h-Indazole-5-carboxylic acid,4,7-dihydro-2-methyl-7-(3-methylbutyl)-4-oxo-,ethyl ester
  • 2-(4-Iodo-3-methylbenzenesulfonamido)benzoic acid
  • (4-(((4,5-Dihydrothiazol-2-yl)thio)methyl)piperidin-1-yl)(thiophen-2-yl)methanone
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