L-arginine

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Names

[ CAS No. ]:
74-79-3

[ Name ]:
L-arginine

[Synonym ]:
L-Arginine
L-ornithine, N-(diaminomethylene)-
MFCD00002635
H-L-ARG-OH
L-Argnie
(L)-Arginine
L-ARG-OH
L-arginie
AGRININE
arginine
L(+)-Arginine
L-Arginine (9CI)
QVYZ3MYZUM &&L or S Form
FEMA 3819
Pentanoic acid, 2-amino-5-[(aminoiminomethyl)amino]-, (S)-
EINECS 200-811-1
ARGININE, L-
L-a-Amino-d-guanidinovaleric Acid
L-Norvaline, 5-[(aminoiminomethyl)amino]-
(2S)-2-Amino-5-carbamimidamidopentanoic acid
H-ARG-OH
S-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid
l-arginin
Arginine, L- (8CI)
Arginine (VAN)
l-arg
5-[(Aminoiminomethyl)amino]-L-norvaline
Arg
N5-(Aminoiminomethyl)-L-ornithine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
367.6±52.0 °C at 760 mmHg

[ Melting Point ]:
222 °C (dec.)(lit.)

[ Molecular Formula ]:
C6H14N4O2

[ Molecular Weight ]:
174.201

[ Flash Point ]:
176.1±30.7 °C

[ Exact Mass ]:
174.111679

[ PSA ]:
125.22000

[ LogP ]:
-1.79

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.601

[ Water Solubility ]:
148.7 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CF1934200
CHEMICAL NAME :
Arginine, L-
CAS REGISTRY NUMBER :
74-79-3
BEILSTEIN REFERENCE NO. :
1725413
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C6-H14-N4-O2
MOLECULAR WEIGHT :
174.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3074 No. of Facilities: 685 (estimated) No. of Industries: 3 No. of Occupations: 14 No. of Employees: 19298 (estimated) No. of Female Employees: 15719 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CF1934200

[ HS Code ]:
2922499990

Synthetic Route

Precursor & DownStream

Precursor

  • DL-Arginine
  • Fmoc-Arg-OH
  • benzyl ((S)-1-(((S)-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)carbamate
  • Z-ARG(NO2)-OH
  • Z(OMe)-Arg(MBS)-OH
  • Z-Arg(Tos)-OH.CHA
  • H-Gly-Arg-OH

DownStream

  • (5S)-5-[(Dimethylamino)methyl]-1-{[hydroxy(methoxy)phosphoryl]oxy }-4,5-dihydro-1H-imidazol-2-amine
  • D-(+)-Octopine
  • (+)-4-CHLOROTARTRANILICACID
  • 2-Guanidinoacetic acid
  • L-Ornithine
  • L-Citruline
  • Tos-L-Arg-NH2 * HCl
  • 4-Guanidinobutanoic acid
  • 4-guanidinobutanal
  • Succinic acid

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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J. Gen. Virol. 95(Pt 8) , 1689-700, (2014)

Hepatitis E virus (HEV), a major cause of acute viral hepatitis across the world, is a non-enveloped, plus-strand RNA virus. Its genome codes three proteins, pORF1 (multifunctional polyprotein), pORF2...

Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.

Arch. Biochem. Biophys. 550-551 , 58-66, (2014)

The mechanism of Mycobacterium smegmatis G (MbsG), a flavin-dependent l-lysine monooxygenase, was investigated under steady-state and rapid reaction conditions using primary and solvent kinetic isotop...

Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy.

J. Neurosci. 35 , 14842-60, (2015)

Tau accumulation remains one of the closest correlates of neuronal loss in Alzheimer's disease. In addition, tau associates with several other neurodegenerative diseases, collectively known as tauopat...


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Related Compounds

  • L-Arginine HCl
  • L-Arginine-2,3-3H
  • L-Arginine malate
  • L-Arginine malate
  • L-Arginine acetate
  • L-Arginine Orotate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine