Acetamide,2-hydroxy-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
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Names
[ CAS No. ]:
74515-40-5
[ Name ]:
Acetamide,2-hydroxy-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
[Synonym ]:
Acetamide,2-hydroxy-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,(S)
2-hydroxy-n-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
Colchifoline
N-(2-hydroxyacetyl)deacetylcolchicine
Chemical & Physical Properties
[ Density]:
1.31g/cm3
[ Boiling Point ]:
768.9ºC at 760 mmHg
[ Molecular Formula ]:
C22H25NO7
[ Molecular Weight ]:
415.43600
[ Flash Point ]:
418.8ºC
[ Exact Mass ]:
415.16300
[ PSA ]:
103.32000
[ LogP ]:
2.23490
[ Index of Refraction ]:
1.601
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC4010000
- CHEMICAL NAME :
- Acetamide, 2-hydroxy-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy -9-oxobenzo(a)heptale n- 7-yl)-, (S)-
- CAS REGISTRY NUMBER :
- 74515-40-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H25-N-O7
- MOLECULAR WEIGHT :
- 415.48
- WISWESSER LINE NOTATION :
- T B677 MV&T&J CO1 DO1 EO1 JMV1Q NO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1620 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983