Acetamide,2-hydroxy-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

Modify Date: 2024-04-05 20:14:54

Acetamide,2-hydroxy-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]- structure	Common Name	Acetamide,2-hydroxy-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
	CAS Number	74515-40-5	Molecular Weight	415.43600
	Density	1.31g/cm3	Boiling Point	768.9ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₅NO₇	Melting Point	N/A
	MSDS	N/A	Flash Point	418.8ºC

Name	2-hydroxy-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Synonym	More Synonyms

Density	1.31g/cm3
Boiling Point	768.9ºC at 760 mmHg
Molecular Formula	C₂₂H₂₅NO₇
Molecular Weight	415.43600
Flash Point	418.8ºC
Exact Mass	415.16300
PSA	103.32000
LogP	2.23490
Index of Refraction	1.601
InChIKey	DIELAJDYLJKYSH-UHFFFAOYSA-N
SMILES	COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)CO)CC2

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AC4010000

CHEMICAL NAME :: Acetamide, 2-hydroxy-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy -9-oxobenzo(a)heptale n- 7-yl)-, (S)-

CAS REGISTRY NUMBER :: 74515-40-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H25-N-O7

MOLECULAR WEIGHT :: 415.48

WISWESSER LINE NOTATION :: T B677 MV&T&J CO1 DO1 EO1 JMV1Q NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1620 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983

Glycolic acid

CAS#:79-14-1

Trimethylcolchi...

CAS#:3476-50-4

~27%

Acetamide,2-hyd...

CAS#:74515-40-5

Literature: Crielaard, Bart J.; Van Der Wal, Steffen; Le, Huong Thu; Bode, Alois T.L.; Lammers, Twan; Hennink, Wim E.; Schiffelers, Raymond M.; Fens, Marcel H.A.M.; Storm, Gert European Journal of Pharmaceutical Sciences, 2012 , vol. 45, # 4 p. 429 - 435

Colchicine

CAS#:64-86-8

Acetamide,2-hyd...

CAS#:74515-40-5

2-Methyl-2-prop...

CAS#:186374-95-8

Acetamide,2-hyd...

CAS#:74515-40-5

N-Boc-colchicine

CAS#:186374-94-7

Acetamide,2-hyd...

CAS#:74515-40-5

Precursor 4
CAS#:79-14-1 Glycolic acid CAS#:3476-50-4 Trimethylcolchi... CAS#:64-86-8 Colchicine CAS#:186374-94-7 N-Boc-colchicine
DownStream 0

Acetamide,2-hydroxy-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,(S)

2-hydroxy-n-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

Colchifoline

N-(2-hydroxyacetyl)deacetylcolchicine

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Acetamide,2-hydroxy-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.