Hydroxychloroquine sulfate
Suppliers
Names
[ CAS No. ]:
747-36-4
[ Name ]:
Hydroxychloroquine sulfate
[Synonym ]:
2-[{4-[(7-Chloro-4-quinolinyl)amino]pentyl}(ethyl)amino]ethanol sulfate (1:1)
2-[{4-[(7-Chlorchinolin-4-yl)amino]pentyl}(ethyl)amino]ethanolsulfat(salt)
EINECS 212-019-3
Hydroxychloroquine Sulfate
Plaquenil
Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol,sulfuric acid
TCMDC-123987
Hydroxychloroquine Sulphate
2-[{4-[(7-Chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol sulfate (1:1)
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol sulfate (salt)
MFCD00078203
Ercoquin
Quensyl
Chemical & Physical Properties
[ Boiling Point ]:
516.7ºC at 760 mmHg
[ Melting Point ]:
240 °C
[ Molecular Formula ]:
C18H28ClN3O5S
[ Molecular Weight ]:
433.950
[ Flash Point ]:
266.3ºC
[ Exact Mass ]:
433.143829
[ PSA ]:
131.37000
[ LogP ]:
4.28400
[ Storage condition ]:
Refrigerator
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KK3342500
- CAS REGISTRY NUMBER :
- 747-36-4
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Cardiac - other changes Lungs, Thorax, or Respiration - acute pulmonary edema
- REFERENCE :
- JATOD3 Journal of Analytical Toxicology. (Preston Pub. Inc., POB 48312, Niles, IL 60648) V.1- 1977- Volume(issue)/page/year: 14,186,1990
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H319
[ Precautionary Statements ]:
P280-P301 + P312 + P330-P305 + P351 + P338-P337 + P313
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
37/39-26
[ RIDADR ]:
3276
[ WGK Germany ]:
3
[ RTECS ]:
KK3342500
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2933499090
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Interferon Cytokine Res. 35(3) , 143-56, (2015)
Hydroxychloroquine (HCQ) is an antimalarial drug also used in treating autoimmune diseases. Its antiviral activity was demonstrated in restricting HIV infection in vitro; however, the clinical implica...
Lupus 24(1) , 32-41, (2014)
Quinine, a quinoline derivative, is an ancient antipyretic drug with antimalarial properties that has been phased out by more effective synthetic candidates. In previous studies we discovered that hyd...
Autoimmun. Rev. 13(10) , 1055-63, (2014)
Introduction B-cell depletion with rituximab (RTX) is widely used to treat autoimmune diseases, especially as second-line therapy for immune thrombocytopenia (ITP). The incidence of RTX-induced hypoga...