4-Amidinophenylmethanesulfonyl fluoride hydrochloride

[ Boiling Point ]:
405.2ºC at 760 mmHg

[ Melting Point ]:
~205 °C (dec.)

[ Molecular Formula ]:
C₈H₁₀ClFN₂O₂S

[ Molecular Weight ]:
252.69

[ Flash Point ]:
198.8ºC

[ Exact Mass ]:
252.013550

[ PSA ]:
92.39000

[ LogP ]:
3.45280

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems.

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925290090

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

In vivo pharmacological characterization of TAK-063, a potent and selective phosphodiesterase 10A inhibitor with antipsychotic-like activity in rodents.

J. Pharmacol. Exp. Ther. 352(3) , 471-9, (2015)

Phosphodiesterase 10A (PDE10A) is a cAMP/cGMP phosphodiesterase highly expressed in medium spiny neurons (MSNs) in the striatum. We evaluated the in vivo pharmacological profile of a potent and select...

Zinc binding activity of human metapneumovirus M2-1 protein is indispensable for viral replication and pathogenesis in vivo.

J. Virol. 89 , 6391-405, (2015)

Human metapneumovirus (hMPV) is a member of the Pneumovirinae subfamily in the Paramyxoviridae family that causes respiratory tract infections in humans. Unlike members of the Paramyxovirinae subfamil...

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription.

FEBS Lett. 589(4) , 532-9, (2015)

APPL1 is a multifunctional endocytic adaptor which acts at different steps of various signaling pathways. Here we report that APPL1 interacts with Dvl2, a protein known to activate the canonical and n...

More Articles