Fluorescein-5-maleimide

Suppliers

Names

[ Name ]:
Fluorescein-5-maleimide

[Synonym ]:
1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)-
1H-Pyrrole-2,5-dione,1-(3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)
Fluorescein-5-maleimide
MFCD00077345
5-Maleimido-fluorescein
5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
fluorescetin-5-maleimide
1-(3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione
N-fluorescein-5-yl maleimide
1-(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione
Fluorescein maleimide
1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
769.1±60.0 °C at 760 mmHg

[ Melting Point ]:
>275ºC (dec.)

[ Molecular Formula ]:
C₂₄H₁₃NO₇

[ Molecular Weight ]:
427.362

[ Flash Point ]:
418.9±32.9 °C

[ Exact Mass ]:
427.069214

[ PSA ]:
113.37000

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.835

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Analysis of tryptophan residues in the staphylococcal multidrug transporter QacA reveals long-distance functional associations of residues on opposite sides of the membrane.

J. Bacteriol. 190(7) , 2441-9, (2008)

Tryptophan residues can possess a multitude of functions within a multidrug transport protein, e.g., mediating interactions with substrates or distal parts of the protein, or fulfilling a structural r...

Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process.

J. Am. Chem. Soc. 130(20) , 6351-61, (2008)

The fluorescein-labeled E166C mutant of the PenPC beta-lactamase (E166Cf) represents a successful model in the construction of "switch-on" fluorescent biosensors from nonallosteric proteins (Chan P.-H...

Accurate high-throughput structure mapping and prediction with transition metal ion FRET.

Structure 21(1) , 9-19, (2013)

Mapping the landscape of a protein's conformational space is essential to understanding its functions and regulation. The limitations of many structural methods have made this process challenging for ...