Fluorescein-5-maleimide

Modify Date: 2024-01-07 15:04:11

Fluorescein-5-maleimide Structure
Fluorescein-5-maleimide structure
Common Name Fluorescein-5-maleimide
CAS Number 75350-46-8 Molecular Weight 427.362
Density 1.7±0.1 g/cm3 Boiling Point 769.1±60.0 °C at 760 mmHg
Molecular Formula C24H13NO7 Melting Point >275ºC (dec.)
MSDS Chinese USA Flash Point 418.9±32.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Fluorescein-5-maleimide


Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm).

 Names

Name 1-(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)pyrrole-2,5-dione
Synonym More Synonyms

 Fluorescein-5-maleimide Biological Activity

Description Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm).
Related Catalog

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 769.1±60.0 °C at 760 mmHg
Melting Point >275ºC (dec.)
Molecular Formula C24H13NO7
Molecular Weight 427.362
Flash Point 418.9±32.9 °C
Exact Mass 427.069214
PSA 113.37000
LogP 1.85
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.835

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synthetic Route

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Fluorescein-5-maleimide Structure

Fluorescein-5-m...

CAS#:75350-46-8

Literature: Synthesis, , # 7 p. 999 - 1002

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles26

More Articles
Analysis of tryptophan residues in the staphylococcal multidrug transporter QacA reveals long-distance functional associations of residues on opposite sides of the membrane.

J. Bacteriol. 190(7) , 2441-9, (2008)

Tryptophan residues can possess a multitude of functions within a multidrug transport protein, e.g., mediating interactions with substrates or distal parts of the protein, or fulfilling a structural r...

Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process.

J. Am. Chem. Soc. 130(20) , 6351-61, (2008)

The fluorescein-labeled E166C mutant of the PenPC beta-lactamase (E166Cf) represents a successful model in the construction of "switch-on" fluorescent biosensors from nonallosteric proteins (Chan P.-H...

Accurate high-throughput structure mapping and prediction with transition metal ion FRET.

Structure 21(1) , 9-19, (2013)

Mapping the landscape of a protein's conformational space is essential to understanding its functions and regulation. The limitations of many structural methods have made this process challenging for ...

 Synonyms

1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)-
1H-Pyrrole-2,5-dione,1-(3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)
Fluorescein-5-maleimide
MFCD00077345
5-Maleimido-fluorescein
5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
fluorescetin-5-maleimide
1-(3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione
N-fluorescein-5-yl maleimide
1-(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione
Fluorescein maleimide
1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-