2-Methyl-1H-indol-5-amine

Names

[ CAS No. ]:
7570-49-2

[ Name ]:
2-Methyl-1H-indol-5-amine

[Synonym ]:
1H-Indol-5-amine, 2-methyl-
2-Methyl-1H-indol-5-amine
MFCD02093426

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
357.3±22.0 °C at 760 mmHg

[ Melting Point ]:
153-157 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀N₂

[ Molecular Weight ]:
146.189

[ Flash Point ]:
197.1±9.5 °C

[ Exact Mass ]:
146.084396

[ PSA ]:
41.81000

[ LogP ]:
1.16

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.720

[ Storage condition ]:
Freezer

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Articles

Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by e...