3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE

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Names

[ CAS No. ]:
75792-87-9

[ Name ]:
3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE

[Synonym ]:
6-(2-thienyl)pyridazine-3-ylhydrazine
3-Hydrazino-6-(2-thienyl)pyridazine
3-hydrazinyl-6-(thiophen-2-yl)pyridazine
Pyridazine,3-hydrazino-6-(2-thienyl)
3-hydrazino-6-thien-2-ylpyridazine

Chemical & Physical Properties

[ Density]:
1.4g/cm3

[ Boiling Point ]:
466.8ºC at 760 mmHg

[ Molecular Formula ]:
C8H8N4S

[ Molecular Weight ]:
192.24100

[ Flash Point ]:
236.1ºC

[ Exact Mass ]:
192.04700

[ PSA ]:
92.07000

[ LogP ]:
2.26400

[ Index of Refraction ]:
1.714

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR6048000
CHEMICAL NAME :
Pyridazine, 3-hydrazino-6-(2-thienyl)-
CAS REGISTRY NUMBER :
75792-87-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H8-N4-S
MOLECULAR WEIGHT :
192.26
WISWESSER LINE NOTATION :
T6NNJ CMZ F- BT5SJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,59,1981

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-chloro-6-(2'-thienyl)pyridazine
  • 6-(2-THIENYL)-3(2H)-PYRIDAZINONE
  • 2-Thiophenebutanoicacid, g-oxo-
  • 4,5-Dihydro-6-(2-thienyl)-3(2H)-pyridazinone

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-Hydrazino-6-((2-hydroxypropyl)methylamino)pyridazine dihydrochloride
  • 3-Hydrazino-6-[(2-hydroxypropyl)amino]pyridazine
  • 3-Piperazin-1-yl-6-(2-thienyl)pyridazine
  • 3-[6-(2-Thienyl)imidazo[2,1-b][1,3]thiazol-3-yl]propanoic acid
  • [6-(2-methylimidazol-1-yl)pyridazin-3-yl]hydrazine
  • [6-(2-ethylimidazol-1-yl)pyridazin-3-yl]hydrazine