Rhynchophylline
Suppliers
Names
[ CAS No. ]:
76-66-4
[ Name ]:
Rhynchophylline
[Synonym ]:
Methyl-(7β,16E,20α)-16-(methoxymethyliden)-2-oxocorynoxan-17-oat
Methyl (7β,16E,20α)-16-(methoxymethylene)-2-oxocorynoxan-17-oate
Methyl (16E)-16-(methoxymethylene)-2-oxocorynoxan-17-oate
Mitrinermine
Rhyncophylline
mitrinermin
Methyl (2E)-2-[(3R,6'R,7'S,8a'S)-6'-ethyl-2-oxo-1,2,2',3',6',7',8',8a'-octahydro-5'H-spiro[indole-3,1'-indolizin]-7'-yl]-3-methoxyacrylate
Methyl (7β,16E,20α)-2-hydroxy-17-methoxy-1,2-didehydrocorynox-16-en-16-carboxylate
Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,3S,6'S,7'S,8'aS)-
methyl (7β,16E,20α)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate
Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,3R,6'R,7'S,8'aS)-
Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-2',3',6',7',8',8'a-hexahydro-2-hydroxy-α-(methoxymethylene)-, methyl ester, (αE,3R,6'R,7'S,8'aS)-
rhynchophyllin
RHYNCHOLPHYLLINE
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
560.8±50.0 °C at 760 mmHg
[ Melting Point ]:
216°; mp 197-199° (Ban et al., loc. cit.)
[ Molecular Formula ]:
C22H28N2O4
[ Molecular Weight ]:
384.469
[ Flash Point ]:
293.0±30.1 °C
[ Exact Mass ]:
384.204895
[ PSA ]:
67.87000
[ LogP ]:
3.31
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.596
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GN1600000
- CHEMICAL NAME :
- Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7- beta,16E,20-alpha)-
- CAS REGISTRY NUMBER :
- 76-66-4
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H28-N2-O4
- MOLECULAR WEIGHT :
- 384.52
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 134 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 94,17,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 94,17,1989
Safety Information
[ Safety Phrases ]:
S24/25
[ RTECS ]:
GN1600000
[ HS Code ]:
29399990