diethylbut-2-indioat

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Names

[ CAS No. ]:
762-21-0

[ Name ]:
diethylbut-2-indioat

[Synonym ]:
Diethyl 2-butynedioate
Diethyl acetylenedicarboxylate
Bis-(Ethoxycarbonyl)acetylene
Di-Ethyl acetylenedicarboxylate
2-Butynedioic acid, diethyl ester
Acetylenedicarboxylic acid, diethyl ester
diethyl but-2-ynedioate
EINECS 212-095-8
MFCD00009186
diethylbut-2-indioat

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
233.9±0.0 °C at 760 mmHg

[ Melting Point ]:
1-3 °C

[ Molecular Formula ]:
C8H10O4

[ Molecular Weight ]:
170.163

[ Flash Point ]:
94.4±0.0 °C

[ Exact Mass ]:
170.057907

[ PSA ]:
52.60000

[ LogP ]:
2.57

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.452

[ Storage condition ]:
0-6°C

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S25

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29171990

Synthetic Route

Precursor & DownStream

Precursor

  • diethyl 2,3-dibromo-fumarate
  • Ethanol
  • 2-Butynedioate, potassium salt (1:1)
  • 2-Butynedioic acid
  • (2,2'-bipyridine)(diethyl acetylenedicarboxylate)copper(I) hexafluorophosphate
  • (4,4'-dimethyl-2,2'-bipyridine)(diethyl acetylenedicarboxylate)copper(I) hexafluoroantimonate
  • benzene
  • diethyl meso-1,2-dibromosuccinate
  • Sodium ethoxide

DownStream

  • 4-Methylphthalic acid
  • 2-MORPHOLIN-4-YL-4-PHENYL-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
  • 1,1':4',1'':4'',1''':4''',1''''-Quinquephenyl
  • Diethyl 2,3-quinolinedicarboxylate
  • diethyl 3-(methylcarbamoyl)-1,2-oxazole-4,5-dicarboxylate
  • diethyl 2-[(2-nitrophenyl)hydrazinylidene]butanedioate
  • diethyl (Z)-2-[bis(2-chloroethyl)amino]but-2-enedioate
  • 3-Methylbut-1-ene

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Enhanced toxicity of the protein cross-linkers divinyl sulfone and diethyl acetylenedicarboxylate in comparison to related monofunctional electrophiles.

Chem. Res. Toxicol. 24(9) , 1457-9, (2011)

Previously, we determined that diethyl acetylenedicarboxylate (DAD), a protein cross-linker, was significantly more toxic than analogous monofunctional electrophiles. We hypothesized that other protei...

3,4,5-Trisubstituted Furan-2(5H)-one Derivatives: Efficient one-pot Synthesis and Evaluation of Cytotoxic Activity.

Drug Res. (Stuttg.) , (2014)

A series of 3,4,5-trisubstituted 2(5H)-furanone derivatives was synthesized through one-pot reaction of amines, aldehydes and diethyl acetylenedicarboxylate. Silica sulfuric acid efficiently catalyzes...

Diels-Alder reactivity of polycyclic aromatic hydrocarbon bay regions: implications for metal-free growth of single-chirality carbon nanotubes.

J. Am. Chem. Soc. 131(44) , 16006-7, (2009)

A soluble bisanthene derivative, 4,11-dimesitylbisanthene, has been synthesized in three steps from bianthrone. In hot toluene, this bisanthene undergoes a clean Diels-Alder reaction with diethyl acet...


More Articles


Related Compounds

  • N,N'-diethylbut-2-enylenediamine
  • N,N-diethylbut-2-enamide
  • N,N-diethylbut-2-en-1-amine
  • (Z)-2,3-diethylbut-2-enedioic acid,1-ethenyl-3-methylimidazol-3-ium,iodide
  • 4-cyclohexyloxy-N,N-diethylbut-2-yn-1-amine
  • N-allyl-N,N-diethylbut-2-yn-1-aminium bromide