(+)-MK 801 Maleate

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Names

[ Name ]:
(+)-MK 801 Maleate

[Synonym ]:
5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)-, (2Z)-2-butenedioate (1:1)
Dizocipine maleate
(+)-MK 801 maleate
Dizocilpine hydrogen maleate
(+)-10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-diyldiammonium maleate
(1S,9R)-1-Methyl-16-azatetracyclo[7.6.1.0.0]hexadeca-2,4,6,10,12,14-hexaene (2Z)-2-butenedioate (1:1)
(1S,9R)-1-Methyl-16-azatetracyclo[7.6.1.0.0]hexadeca-2,4,6,10,12,14-hexaene (2Z)-but-2-enedioate (1:1)
DIZOCILPINE MALEATE
MFCD00082465
(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (Z)-2-Butenedioate (1:1)
Neurogard
(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene (2Z)-but-2-enedioate (1:1)
EINECS 278-614-5

Chemical & Physical Properties

[ Boiling Point ]:
541ºC at 760 mmHg

[ Melting Point ]:
183-185ºC

[ Molecular Formula ]:
C₂₀H₁₉NO₄

[ Molecular Weight ]:
337.369

[ Flash Point ]:
281ºC

[ Exact Mass ]:
337.131409

[ PSA ]:
86.63000

[ LogP ]:
3.19110

[ Storage condition ]:
-20℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
HP1093575

Articles

Role of ionotropic glutamate receptors in delay and probability discounting in the rat.

Psychopharmacol. Ser. 232(7) , 1187-96, (2015)

Discounting of delayed and probabilistic reinforcement is linked to increased drug use and pathological gambling. Understanding the neurobiology of discounting is important for designing treatments fo...

The role of the glutamatergic NMDA receptor in nanosilver-evoked neurotoxicity in primary cultures of cerebellar granule cells.

Toxicology 315 , 38-48, (2014)

Nanoparticles are known to enter the vertebrate brain, but little is known about their neurotoxicity. The aim of this study is to investigate mechanisms of the contribution of AgNPs to neuronal cell d...

The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis.

J. Neural Transm. Gen. Sect. 117(11) , 1319-25, (2010)

Tofisopam is a member of the 2,3-benzodiazepine compound family which is marketed for the treatment of anxiety in some European countries. In contrast to classical 1,4-benzodiazepines, the compound do...

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