SKF 100398
Suppliers
Names
[ CAS No. ]:
77453-01-1
[ Name ]:
SKF 100398
[Synonym ]:
M.W. 1136.41 C53H77N13O11S2
type 1 arginine vasopressin antagonist
(d(CH2)51,Tyr(Et)2,Val4,Arg8)-Vasopressin
Chemical & Physical Properties
[ Density]:
1.44g/cm3
[ Molecular Formula ]:
C53H77N13O11S2
[ Molecular Weight ]:
1136.39000
[ Exact Mass ]:
1135.53000
[ PSA ]:
431.92000
[ LogP ]:
4.60970
[ Index of Refraction ]:
1.676
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H332
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
20
[ Safety Phrases ]:
36
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Articles
Proc. Natl. Acad. Sci. U. S. A. 92(4) , 1013-7, (1995)
Water excretion by the kidney is regulated by the peptide hormone vasopressin. Vasopressin increases the water permeability of the renal collecting duct cells, allowing more water to be reabsorbed fro...
Nature 337(6208) , 648-51, (1989)
Growth factors raise intracellular pH (pHi) by stimulating Na+/H+ exchange in the absence of HCO3-. In mutant cells that lack the Na+/H+ exchange activity, this alkalinization does not occur, and the ...
Am. J. Physiol. 262 , F546-F553, (1992)
Vasopressin receptors in distal segments of the rat nephron were identified in isolated tubules using two labeled ligands: the [1-(beta-mercapto-beta,beta-cyclopentamethylenepropionic acid), 2-(O-meth...