Nepafenac

Suppliers

Names

[ CAS No. ]:
78281-72-8

[ Name ]:
Nepafenac

[Synonym ]:
Benzeneacetamide, 2-amino-3-benzoyl-
Nevanac
2-(2-Amino-3-benzoylphenyl)acetamide
Nepafenac
Nepafanac
2-Amino-3-benzoylbenzeneacetamide
2-[2-amino-3-(phénylcarbonyl)phényl]acétamide
AL 6515
AHR 9434
2-[2-Amino-3-(phenylcarbonyl)phenyl]acetamid
2-[2-amino-3-(phenylcarbonyl)phenyl]acetamide
2-Amino-3-benzoyl-phenylacetamide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
562.5±50.0 °C at 760 mmHg

[ Melting Point ]:
177-181ºC

[ Molecular Formula ]:
C15H14N2O2

[ Molecular Weight ]:
254.284

[ Flash Point ]:
294.0±30.1 °C

[ Exact Mass ]:
254.105530

[ PSA ]:
86.18000

[ LogP ]:
0.73

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.641

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Amino-3-benzoyl-.alpha.-(methylthio)benzeneacetamide
  • 2-Aminobenzophenone

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Use of nepafenac (Nevanac) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections.

Clin. Ophthalmol. 4 , 1249-52, (2010)

The purpose of this study is to determine the efficacy of combining topical nepafenac with monthly intravitreal injections of ranibizumab or bevacizumab in the treatment of recalcitrant exudative macu...


More Articles

Related Compounds

  • NEPAFENAC
  • Nepafenac D5
  • Nepafenac Impurity 2
  • Nepafenac IMpurity D
  • 5-bromo-N-(5-oxopyrrolidin-3-yl)nicotinamide
  • N-(5-oxopyrrolidin-3-yl)pivalamide
  • N-(5-oxopyrrolidin-3-yl)adamantane-1-carboxamide
  • 2-(ethylthio)-N-(5-oxopyrrolidin-3-yl)benzamide
  • 2,4-dimethyl-N-(5-oxopyrrolidin-3-yl)thiazole-5-carboxamide
  • N-(5-oxopyrrolidin-3-yl)pyrazine-2-carboxamide
  • N-(5-oxopyrrolidin-3-yl)cyclobutanecarboxamide
  • N-(5-oxopyrrolidin-3-yl)picolinamide
  • N-(5-oxopyrrolidin-3-yl)-4-phenoxybenzamide
  • 3-(dimethylamino)-N-(5-oxopyrrolidin-3-yl)benzamide
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