20-HETE

Suppliers

Names

[ Name ]:
20-HETE

[Synonym ]:
20-hydroxy-5,8,11,14-eicosatetraenoic acid
20-HETE
20-Hydroxyicosatetraenoic acid
5,8,11,14-Eicosatetraenoic acid, 20-hydroxy-, (5Z,8Z,11Z,14Z)-
DSR-II-247-30
(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid
20-Hydroxyeicosatetraenoic acid
20-Hydroxyicosatetraenoate
20-Hydroxy arachidonic acid
(5Z,8Z,11Z,14Z)-20-Hydroxy-5,8,11,14-icosatetraenoic acid

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
482.0±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₃

[ Molecular Weight ]:
320.47

[ Flash Point ]:
259.4±21.9 °C

[ Exact Mass ]:
320.235138

[ PSA ]:
57.53000

[ LogP ]:
4.91

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.515

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319

[ Precautionary Statements ]:
P210-P305 + P351 + P338-P370 + P378-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
11-36/37/38

[ Safety Phrases ]:
16-26-36

[ RIDADR ]:
UN 1170 3/PG 2

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(5Z,8Z,11Z,14Z)-20-hydroxyeicosa-5,8,11,14-tetraenoic acid methyl ester
methyl 14-oxotetradeca-5,8,11-trienoate
14,15-dihydroxy-eicosa-5Z,8Z,11Z-trienoic acid methyl ester
14,15-Epoxyeicosatrienoic acid methylester
4-Penten-1-ol
methyl 15-bromopentadeca-5(Z),8(Z),11(Z),14(Z)-tetraenoate
methyl 15,15-dibromopentadeca-5(Z),8(Z),11(Z)-tetraenoate

DownStream

Articles

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...

The human serum metabolome.

PLoS ONE 6(2) , e16957, (2011)

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the m...

IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.

J. Cereb. Blood Flow Metab. 34(12) , 1887-97, (2014)

Aging impairs autoregulatory protection in the brain, exacerbating hypertension-induced cerebromicrovascular injury, neuroinflammation, and development of vascular cognitive impairment. Despite the im...