KYP 2047

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Names

[ CAS No. ]:
796874-99-2

[ Name ]:
KYP 2047

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₅N₃O₂

[ Molecular Weight ]:
339.43

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Articles

A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.

Br. J. Pharmacol. 166(3) , 1097-113, (2012)

The aggregation of α-synuclein is connected to the pathology of Parkinson's disease and prolyl oligopeptidase (PREP) accelerates the aggregation of α-synuclein in vitro. The aim of this study was to i...

2-(diethylamino)-N-methyl-N-[1-(2,4,6-trimethylphenoxy)propan-2-yl]acetamide,hydrochloride
1-[5-(4,5-dimethyl-1H-imidazol-1-yl)pyridin-2-yl]ethan-1-one
2-Ethyl-6-benzoxazolemethanol
(2-(4-Methoxyphenyl)benzo[d]oxazol-5-yl)methanol
(2-(3,4-Dichlorophenyl)benzo[d]oxazol-5-yl)methanol
[3-Methoxy-6-(4-methoxyphenyl)pyridazin-4-yl]boronic acid
B-[4-(Tetrahydro-2-oxo-1(2H)-pyrimidinyl)phenyl]boronic acid
b-(3-Amino-8-hydroxy-1,10-phenanthrolin-2-yl)-boronic acid
4-((3-Hydroxypyrrolidin-1-yl)methyl)phenylboronic acid
(2,2,4,4-Tetramethylthiochroman-6-yl)boronic acid
2,3-Dihydrothieno[3,4-b][1,4]dioxin-5-ylboronic acid

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