KYP 2047

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Names

[ CAS No. ]:
796874-99-2

[ Name ]:
KYP 2047

Chemical & Physical Properties

[ Molecular Formula ]:
C20H25N3O2

[ Molecular Weight ]:
339.43

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Articles

A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.

Br. J. Pharmacol. 166(3) , 1097-113, (2012)

The aggregation of α-synuclein is connected to the pathology of Parkinson's disease and prolyl oligopeptidase (PREP) accelerates the aggregation of α-synuclein in vitro. The aim of this study was to i...


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Related Compounds

  • 2-(diethylamino)-N-methyl-N-[1-(2,4,6-trimethylphenoxy)propan-2-yl]acetamide,hydrochloride
  • Penta-salicyclic Acid
  • 3,4-Dichlorophenyl 4-methylbenzene-1-sulfonate
  • 3-(3-Cyclopropyl-1,2-oxazol-5-yl)furan-2-sulfonyl fluoride
  • 1,3-dimethyl-4-(thiophen-2-yl)-1H-pyrazol-5-ol
  • 4-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-ol
  • 4-(2-methoxyphenyl)-1,3-dimethyl-1H-pyrazol-5-ol
  • 1,3-dimethyl-4-(3-nitrophenyl)-1H-pyrazol-5-ol
  • O-[1-(1H-imidazol-5-yl)ethyl]hydroxylamine
  • 4-(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)benzaldehyde
  • 3-(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)benzoic acid
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