KYP 2047

KYP 2047 Structure
KYP 2047 structure
Common Name KYP 2047
CAS Number 796874-99-2 Molecular Weight 339.43
Density N/A Boiling Point N/A
Molecular Formula C20H25N3O2 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.

Br. J. Pharmacol. 166(3) , 1097-113, (2012)

The aggregation of α-synuclein is connected to the pathology of Parkinson's disease and prolyl oligopeptidase (PREP) accelerates the aggregation of α-synuclein in vitro. The aim of this study was to investigate the effects of a PREP inhibitor, KYP-2047, on α-...