HIRUDIN LEECH, RECOMBINANT

[ Molecular Formula ]:
C₂₈₇H₄₄₀N₈₀O₁₁₀S₆

[ Molecular Weight ]:
7027

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
−70°C

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MR8440000

Contributions of multiple proteases to neurotoxicity in a mouse model of intracerebral haemorrhage.

Brain 132 , 26-36, (2009)

Proteases such as matrix metalloproteinases (MMPs) and thrombin are implicated in intracerebral haemorrhage (ICH) but their interactions amongst one another and interdependency remain to be defined. T...

TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells.

J. Immunol. 196 , 832-45, (2016)

Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy with severe renal injury secondary to an overactive alternative complement pathway (AP). aHUS episodes are often initiated or ...

Differential neuroprotection and risk for bleeding from activated protein C with varying degrees of anticoagulant activity.

Stroke 40(5) , 1864-9, (2009)

Activated protein C (APC), a protease with anticoagulant and cytoprotective activities, protects neurons and endothelium from ischemic injury. Drotrecogin-alfa activated, a hyperanticoagulant form of ...

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