ACRIFLAVINE

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Names

[ CAS No. ]:
8048-52-0

[ Name ]:
ACRIFLAVINE

[Synonym ]:
ACRIFLAVINE
EUFLAVINE
3,6-Diamino-10-methylacridinium chloride - 3,6-acridinediamine (1:1:1)
3,6-Diamino-10-methylacridinium Chloride mixt with 3,6-Acridine Diamine
3,6-Diamino-10-methylacridinium chloride 3,6-acridinediamine (1:1:1)
diacrid
3,6-Diamino-10-methylacridinium chloride 3,6-acridinediamine (1:1)
flavipin
Trypaflavine
Acridinium, 3,6-diamino-10-methyl-, chloride, mixt. with 3,6-acridinediamine
gonacin
3,6-Diamino-10-methylacridinium chloride - acridine-3,6-diamine (1:1:1)
flavine
Neutroflavine
EUFLAVIN
angiflan
Neutral Acriflavine
flavisept
isravin
MFCD00064307

Chemical & Physical Properties

[ Melting Point ]:
179-181 °C

[ Molecular Formula ]:
C14H14ClN3

[ Molecular Weight ]:
259.73

[ PSA ]:
120.85000

[ LogP ]:
3.86310

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR9660000
CHEMICAL NAME :
Acridinium, 3,6-diamino-10-methyl-, chloride mixed with 3,6-acridinediamine
CAS REGISTRY NUMBER :
8048-52-0
LAST UPDATED :
199706
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C14-H14-N3.Cl.C13-H11-N3
MOLECULAR WEIGHT :
469.03
WISWESSER LINE NOTATION :
T C666 BKJ B1 EZ MZ &G &T C666 BNJ EZ MZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg/60W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
Dominant lethal test

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
25 mg/L
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 19,55,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 13,31,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 13,31,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1531 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 40 (estimated) No. of Female Employees: 10 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R22;R37/38;R41;R50/53

[ Safety Phrases ]:
S26-S39-S60-S61

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
AR9660000

[ HS Code ]:
38249064

Customs

[ HS Code ]: 38249064

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Related Compounds

  • Acriflavine
  • ACRIFLAVINE HCL
  • Acriflavine hydrochloride
  • Acriflavine (component of)