COUMACHLOR

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Names

[ CAS No. ]:
81-82-3

[ Name ]:
COUMACHLOR

[Synonym ]:
UNII:UCD8XZW42P
3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxy-2H-1-benzopyran-2-one (9CI)
MFCD00012094
2H-1-Benzopyran-2-one, 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-
3-(a-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin
tomorin
3-[(1RS)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxycoumarin
3-(a-p-Chlorophenyl-b-acetylethyl)-4-hydroxycoumarin
3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one
Coumachlor
Geigy Rodenticide Exp.332
FAMARIN
rac-3-[(1R)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one
3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-chromen-2-one
ratilan
P-CHLOROWARFARIN
cumachloor
kumachlor
(±)-3-(1-(p-Chlorophenyl)-3-oxobutyl)-4-hydroxycoumarin
EINECS 201-378-1
(±)-Coumachlor

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
543.1±50.0 °C at 760 mmHg

[ Melting Point ]:
168-170 °C(lit.)

[ Molecular Formula ]:
C₁₉H₁₅ClO₄

[ Molecular Weight ]:
342.773

[ Flash Point ]:
282.3±30.1 °C

[ Exact Mass ]:
342.065887

[ PSA ]:
67.51000

[ LogP ]:
4.01

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.641

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4830000

CHEMICAL NAME :: Coumarin, 3-(alpha-acetonyl-p-chlorobenzyl)-4-hydroxy-

CAS REGISTRY NUMBER :: 81-82-3

BEILSTEIN REFERENCE NO. :: 1689759

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H15-Cl-O4

MOLECULAR WEIGHT :: 342.79

WISWESSER LINE NOTATION :: T66 BOVJ DY1V1&R DG& EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 392 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H373-H412

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R48/22;R52/53

[ Safety Phrases ]:
S37-S61

[ RIDADR ]:
UN 2811 6.1/PG 1

[ WGK Germany ]:
2

[ RTECS ]:
GN4830000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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Commun. Agric. Appl. Biol. Sci. 68(4 Pt B) , 771-87, (2003)

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