5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

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Names

[ CAS No. ]:
81279-39-2

[ Name ]:
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

[Synonym ]:
5'-dimethoxytrityl 2'-tert-butyldimethyl silyl N-isobutyrylguanosine
(2)N-isobutyryl-5'O-dimetoxytrityl-3'O-tert-butyldimethylsilyl guanosine
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine
N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl guanosine
N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
2-N-isobutyryl-2'-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)guanosine
5'-O-dimethoxytrityl-2'-O-tert-butyldimethylsilyl-N2-isobutyryl guanosine

Chemical & Physical Properties

[ Density]:
1.25

[ Molecular Formula ]:
C41H51N5O8Si

[ Molecular Weight ]:
769.95800

[ Exact Mass ]:
769.35100

[ PSA ]:
159.31000

[ LogP ]:
6.87400

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-Butyldimethylsilyl chloride
  • 5'-DMT-ibu-rG
  • 4,4'-Dimethoxytrityl chloride
  • Guanosine
  • 3',5'-O-DTBS-guanosine
  • N-Isobutyrylguanosine

DownStream

  • I-bu-rG Phosphoramidite

Related Compounds

  • 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
  • N-(1-((2R,3R,4R,5R)-5-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-3-((TERT-BUTYLDIMETHYLSILYL)OXY)-4-HYDROXYTETRAHYDROFURAN-2-YL)-2-OXO-1,2-DIHYDROPYRIMIDIN-4-YL)BENZAMIDE
  • 5'-O-DMT-2'-O-MOE-N2-ibu-rG
  • 5'-O-DMT-2'-O-MOE-N4-Bz-rC
  • 5'-O-DMT-2'-O-MOE-N6-Bz-rA
  • 5'-O-DMT-2'-O-MOE-N4-Bz-5-Me-C