5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

Modify Date: 2025-08-31 17:51:11

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine structure	Common Name	5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
	CAS Number	81279-39-2	Molecular Weight	769.95800
	Density	1.25	Boiling Point	N/A
	Molecular Formula	C₄₁H₅₁N₅O₈Si	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides[1].

Name	N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
Synonym	More Synonyms

Description	5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Thomas P Blaisdell, et al. Practical silyl protection of ribonucleosides. Org Lett. 2013 Sep 20;15(18):4710-3.

Density	1.25
Molecular Formula	C₄₁H₅₁N₅O₈Si
Molecular Weight	769.95800
Exact Mass	769.35100
PSA	159.31000
LogP	6.87400

Hazard Codes	Xi

tert-Butyldimethylsilyl chloride structure

tert-Butyldimet...

CAS#:18162-48-6

5'-DMT-ibu-rG structure

5'-DMT-ibu-rG

CAS#:81246-83-5

~61%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

5'-DMT-3'-TBDMS-ibu-rG structure

5'-DMT-3'-TBDMS...

CAS#:81256-89-5

Literature: Wexselblatt, Ezequiel; Katzhendler, Jehoshua; Saleem-Batcha, Raspudin; Hansen, Guido; Hilgenfeld, Rolf; Glaser, Gad; Vidavski, Roee R. Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 12 p. 4485 - 4497

tert-Butyldimethylsilyl chloride structure

tert-Butyldimet...

CAS#:18162-48-6

5'-DMT-ibu-rG structure

5'-DMT-ibu-rG

CAS#:81246-83-5

~74%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Blaisdell, Thomas P.; Lee, Sunggi; Kasaplar, Pinar; Sun, Xixi; Tan, Kian L. Organic Letters, 2013 , vol. 15, # 18 p. 4710 - 4713

4,4'-Dimethoxytrityl chloride structure

4,4'-Dimethoxyt...

CAS#:40615-36-9

2'-O-TBDMS-N2-ibu-rG structure

2'-O-TBDMS-N2-ibu-rG

CAS#:182007-86-9

~88%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Serebryany; Beigelman Nucleosides, nucleotides and nucleic acids, 2003 , vol. 22, # 5-8 p. 1007 - 1009

Guanosine structure

Guanosine

CAS#:118-00-3

~%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Serebryany; Beigelman Nucleosides, nucleotides and nucleic acids, 2003 , vol. 22, # 5-8 p. 1007 - 1009

3',5'-O-DTBS-guanosine structure

3',5'-O-DTBS-gu...

CAS#:126628-29-3

~%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Serebryany; Beigelman Nucleosides, nucleotides and nucleic acids, 2003 , vol. 22, # 5-8 p. 1007 - 1009

2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine structure

2'-O-(tert-buty...

CAS#:401812-99-5

~%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Serebryany; Beigelman Nucleosides, nucleotides and nucleic acids, 2003 , vol. 22, # 5-8 p. 1007 - 1009

N-[9-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]-6-oxo-5H-purin-2-ylidene]-2-methylpropanamide structure

N-[9-[(4aR,6R,7...

CAS#:401813-00-1

~%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Serebryany; Beigelman Nucleosides, nucleotides and nucleic acids, 2003 , vol. 22, # 5-8 p. 1007 - 1009

N-Isobutyrylguanosine structure

N-Isobutyrylgua...

CAS#:64350-24-9

~%

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Structure

5'-O-DMT-2'-O-i...

CAS#:81279-39-2

Literature: Glaser, Gad; Katzhendler, Jehoshua; Hilgenfeld, Rolf; Vidavski, Roee; Wexselblatt, Ezequiel; Prez-Menahemov, Tamar; Kaspy, Ilana Patent: US2011/86813 A1, 2011 ;

Precursor 6
CAS#:18162-48-6 tert-Butyldimet... CAS#:81246-83-5 5'-DMT-ibu-rG CAS#:40615-36-9 4,4'-Dimethoxyt... CAS#:118-00-3 Guanosine
CAS#:126628-29-3 3',5'-O-DTBS-gu... CAS#:64350-24-9 N-Isobutyrylgua...
DownStream 1
CAS#:147201-04-5 I-bu-rG Phospho...

5'-dimethoxytrityl 2'-tert-butyldimethyl silyl N-isobutyrylguanosine

(2)N-isobutyryl-5'O-dimetoxytrityl-3'O-tert-butyldimethylsilyl guanosine

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine

N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl guanosine

N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

2-N-isobutyryl-2'-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)guanosine

5'-O-dimethoxytrityl-2'-O-tert-butyldimethylsilyl-N2-isobutyryl guanosine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
Price: ￥548.0/250mg ￥1298.0/1g
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DC Chemicals Limited
China
Product Name: 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
Price: ￥Inquiry/1g
Purity: 98.9%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-(9-((2R,3R,4R,5R)-5-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-3-((TERT-BUTYLDIMETHYLSILYL)OXY)-4-HYDROXYTETRAHYDROFURAN-2-YL)-6-OXO-6,9-DIHYDRO-1H-PURIN-2-YL)ISOBUTYRAMIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥304/250mg

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