(Trifluoromethyl)trimethylsilane

Names

[ Name ]:
(Trifluoromethyl)trimethylsilane

[Synonym ]:
Silane, trimethyl(trifluoromethyl)-
(trifluoromethyl)-trimethylsilane
Trifluoromethyl(trimethyl)silane
Trimethyl(trifluoromethyl)silane
(Trifluoromethyl)trimethylsilane
MFCD00145454

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
49.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₉F₃Si

[ Molecular Weight ]:
142.19

[ Flash Point ]:
-16.4±27.3 °C

[ Exact Mass ]:
142.042557

[ LogP ]:
1.85

[ Vapour Pressure ]:
313.6±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.328

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Supplemental HS ]:
May form explosive peroxides.

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F:Flammable;Xi:Irritant;

[ Risk Phrases ]:
R11;R19;R36/37

[ Safety Phrases ]:
S16-S33-S39-S26-S36-S29

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Chlorotrimethylsilane
Trifluoromethane
Iodotrifluoromethane
Bromotrifluoromethane (R 13B1)
Phenyl Trifluoromethyl Sulfone
Phenyl Trifluoromethyl Sulfoxide
Trimethylsilyl trifluoroacetate
Trifluoro(methanesulfonyl)methane
((trifluoromethyl)thio)benzene
METHYLMAGNESIUM BROMIDE

DownStream

1-(2-chloropyridin-3-yl)-2,2,2-trifluoroethanone
Benzonitrile, 4-(2,2,2-trifluoro-1-hydroxyethyl)- (9CI)
2,2,2-Trifluoro-1-(pyridin-2-yl)ethanol
1-nitro-3-(3,3,3-trifluoroprop-1-ynyl)benzene
2-(Trifluoromethyl)benzonitrile
1-Nitro-2-(trifluoromethyl)benzene
1,1,1-Trifluoro-4-iodobutane
1,1,1-TRIFLUOROBUTENE-3
1,1,1,5,5,5-Hexafluoropentane
4-Aminobenzotrifluoride

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF.

J. Org. Chem. 71 , 6806, (2006)

Organofluorine compounds are becoming increasingly important in different fields, such as material science, agro chemistry, and the pharmaceutical industry. Nucleophilic trifluoromethylation is one of...