Ketoleucine
Suppliers
Names
[ CAS No. ]:
816-66-0
[ Name ]:
Ketoleucine
[Synonym ]:
2-Oxo-4-methylvaleric acid
α-ketoisocaproic acid
2-Oxoisocaproic acid
2-KETOISOCAPROIC ACID
EINECS 212-435-5
4-Methyl-2-oxopentanoic acid
Pentanoic acid, 4-methyl-2-oxo-
&α;-ketoisocaproic acid
2-keto-4-Methylvaleric acid
4-Methyl-2-oxovaleric Acid
4-methyl-2-oxo-Valeric acid
Ketoleucine
MFCD00066204
α-keto-isocaproic acid
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
190.5±9.0 °C at 760 mmHg
[ Melting Point ]:
8-10 °C
[ Molecular Formula ]:
C6H10O3
[ Molecular Weight ]:
130.142
[ Flash Point ]:
83.3±15.2 °C
[ Exact Mass ]:
130.062988
[ PSA ]:
54.37000
[ LogP ]:
0.17
[ Vapour Pressure ]:
0.2±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.438
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3265 8/PG 3
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2918300090
Synthetic Route
Customs
[ HS Code ]: 2918300090
[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993)
Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...
Biochem. Pharmacol. 80(1) , 104-12, (2010)
The K(+) channel blocker, TEA is known to increase action potential amplitude and insulin secretion of mouse beta-cells when added to a nutrient secretagogue. In the presence of a maximally effective ...
Enzyme Microb. Technol. 49(4) , 321-5, (2011)
This work aims to produce α-ketoisocaproate (KIC) from l-leucine via the free-whole-cell biotransformation of Rhodococcus opacus DSM 43250. The effects of temperature, pH, substrate concentration, cel...