Lumefantrine

Suppliers

Names

[ CAS No. ]:
82186-77-4

[ Name ]:
Lumefantrine

[Synonym ]:
(±)-2-(Dibutylamino)-1-((9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol
(±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol
(Z)-2-(Dibutylamino)-1-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol
Benflumetol
Lumefantrine
2-(Dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
9H-Fluorene-4-methanol, 2,7-dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-, (9Z)-

Chemical & Physical Properties

[ Density]:
1.252

[ Boiling Point ]:
642.5±55.0 °C at 760 mmHg

[ Melting Point ]:
129-131ºC

[ Molecular Formula ]:
C30H32Cl3NO

[ Molecular Weight ]:
528.940

[ Flash Point ]:
342.3±31.5 °C

[ Exact Mass ]:
527.154968

[ PSA ]:
23.47000

[ LogP ]:
11.37

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.634

[ Storage condition ]:
Refrigerator

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.

Immunology 145(1) , 71-81, (2015)

This study examined specific antibody and T-cell responses associated with experimental malaria infection or malaria vaccination, in malaria-naive human volunteers within phase I/IIa vaccine trials, w...

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity.

Malaria Journal 13 , 359, (2014)

Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolis...

Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.

J. Clin. Microbiol. 53 , 3296-303, (2015)

Flow cytometry is an objective method for conducting in vitro antimalarial sensitivity assays with increasing potential for application in field sites. We examined in vitro susceptibility to seven ant...


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Related Compounds

  • Lumefantrine
  • lumefantrine
  • Lumefantrine D18
  • Desbutyl LuMefantrine
  • Artemether-Lumefantrine
  • Desbutyl Lumefantrine D9