4-chloro-2,8-di(trifluoromethyl)quinoline
Suppliers
Names
[ CAS No. ]:
83012-13-9
[ Name ]:
4-chloro-2,8-di(trifluoromethyl)quinoline
[Synonym ]:
4-chloro-2,8-di(trifluoromethyl)quinoline
4-Chloro-2,8-bis(trifluoromethyl)quinoline
EINECS 280-132-5
MFCD00075104
4-Chloro-2,8-bis-trifluoromethyl-quinoline
Quinoline, 4-chloro-2,8-bis(trifluoromethyl)-
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
251.8±35.0 °C at 760 mmHg
[ Melting Point ]:
46-48 °C(lit.)
[ Molecular Formula ]:
C11H4ClF6N
[ Molecular Weight ]:
299.600
[ Flash Point ]:
106.1±25.9 °C
[ Exact Mass ]:
298.993652
[ PSA ]:
12.89000
[ LogP ]:
4.36
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.495
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Eur. J. Med. Chem. 45 , 3374, (2010)
Four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl aniline through multi-step reactions. In the reaction sequence, substituted aniline was cyclized to 4-hydroxy ...