Salvinorin A(Divinorin A)

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Names

[ Name ]:
Salvinorin A(Divinorin A)

[Synonym ]:
Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate
2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-, methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate
Divinorin A
salvonorin A
2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-, methyl ester, (2S,4aR,7R,9S,10aS,10bR)-
Salvinorin
Methyl (2S,4aR,7R,9S,10aS,10bR)-9-acetoxy-2-(3-furyl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate
Salvinorin A
MFCD05664742
Diviner's Sage
Mexican mint
herbal ecstasy

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
563.8±50.0 °C at 760 mmHg

[ Melting Point ]:
238-240ºC

[ Molecular Formula ]:
C₂₃H₂₈O₈

[ Molecular Weight ]:
432.464

[ Flash Point ]:
294.8±30.1 °C

[ Exact Mass ]:
432.178406

[ PSA ]:
109.11000

[ LogP ]:
1.82

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.548

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312 + H332-H319

[ Precautionary Statements ]:
P210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F,Xn

[ Risk Phrases ]:
11-20/21/22-36

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
UN 1648 3 / PGII

[ RTECS ]:
QL6127142

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethanoic anhydride
Salvinorin B
epi-salvinorin B
acetic acid

DownStream

Articles

Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.

J. Pharmacol. Exp. Ther. 350(1) , 69-78, (2014)

The opioid and cannabinoid systems play a crucial role in multiple physiological processes in the central nervous system and in the periphery. Selective opioid as well as cannabinoid (CB) receptor ago...

Regulating a novel drug: an evaluation of changes in use of Salvia divinorum in the first year of Florida's ban.

Int. J. Drug Policy 23(6) , 512-21, (2012)

A plant with dissociative and psychoactive properties began to attract the attention of the media and United States policymakers following a well-publicized suicide in 2006 and reports that the plant ...

Development of an enzyme immunoassay using a monoclonal antibody against the psychoactive diterpenoid salvinorin A.

J. Nat. Prod. 76(9) , 1654-60, (2013)

Salvinorin A (1), the main active constituent in Salvia divinorum, is a highly selective kappa-opioid receptor agonist with hallucinogenic effects, which is regulated in several countries. In the pres...

Salvinorin A Propionate
Salvinorin A Carbamate
3-[(A,A,A-TRIFLUORO-M-TOLYL)OXY]-PYRROLIDINE HYDROCHLORIDE
Benzenemethanol, a,a-dicyclopropyl-4-methoxy-
Benzeneethanol, a,a-diethyl-b-(methylimino)-
Benzeneethanol, a,a-diethyl-b-methoxy-, 1-(4-nitrobenzoate)
tert-Butyl 3-(5-bromo-1,3-dioxoisoindolin-2-yl)azetidine-1-carboxylate
2-Methyl-acrylic acid 10-azido-decyl ester
N-allyl-6-methylpyrazin-2-amine
4-(2,2-Difluorocyclopropyl)-2,2-dimethylbutan-1-ol
6,6-Dimethylspiro[3.3]heptan-2-amine
4,7-Dibromo-1,10-phenanthroline hydrate
2-(9H-Fluoren-2-yl)-malononitrile
1-Fluoro-3-(6-methyl-1,4-oxazepan-4-yl)propan-2-ol
3-(4-Methoxyphenyl)-1-[4-(oxolan-3-yl)-1,4-diazepan-1-yl]propan-1-one
N-((4-hydroxy-4,5,6,7-tetrahydrobenzofuran-4-yl)methyl)-6-(trifluoromethyl)nicotinamide

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