Cetirizine

Suppliers

Names

[ Name ]:
Cetirizine

[Synonym ]:
Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-
(2-{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetic acid
Reactine
CERTIRIZINE 2HCL
Zirtek
acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
Cetirizine
Ceterizine
[(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]acetic acid
Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
vidix
P-071
MFCD00800721
(±)-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid
Cetrizinehydrochloride
Formistin
(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
UNII:YO7261ME24
Zyrlex
(±)-[2-[4-(p-Chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]acetic Acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
542.1±45.0 °C at 760 mmHg

[ Melting Point ]:
110-115°C

[ Molecular Formula ]:
C₂₁H₂₅ClN₂O₃

[ Molecular Weight ]:
388.888

[ Flash Point ]:
281.6±28.7 °C

[ Exact Mass ]:
388.155365

[ PSA ]:
53.01000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.589

[ Storage condition ]:
2-8℃

[ Water Solubility ]:
101 mg/L

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AG0977500

CHEMICAL NAME :: Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)et hoxy)-

CAS REGISTRY NUMBER :: 83881-51-0

LAST UPDATED :: 199606

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H25-Cl-N2-O3

MOLECULAR WEIGHT :: 388.93

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 116 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4525358

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ WGK Germany ]:
3

[ RTECS ]:
AG0977500

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-{2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy}acetaldehyde diethylacetal
Cetirizine Amide
2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride
UNII:PGV947X9B1
Sodium chloroacetate
Cetirizine Dihydrochloride
Chloroacetic acid

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%