1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one

Suppliers

Names

[ CAS No. ]:
84044-26-8

[ Name ]:
1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one

[Synonym ]:
1-Methyl-7-chloro-5-phenyl-3-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one
1-Methyl-7-chloro-5-phenyl-3-acetylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
628ºC at 760 mmHg

[ Molecular Formula ]:
C17H15ClN4O2

[ Molecular Weight ]:
342.78000

[ Flash Point ]:
333.6ºC

[ Exact Mass ]:
342.08800

[ PSA ]:
73.80000

[ LogP ]:
2.28000

[ Index of Refraction ]:
1.665

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG5105000
CHEMICAL NAME :
Benzoic acid, 2-(7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1, 4-benzodiazepin-3-yl) hydrazide
CAS REGISTRY NUMBER :
84044-26-8
LAST UPDATED :
199803
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H19-Cl-N4-O2
MOLECULAR WEIGHT :
418.91

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,617,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzohydrazide
  • 3,7-dichloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one

DownStream

Related Compounds

  • 4-Methyl-2-(4-nitro-1-naphthalenyl)-5-phenyl-2H-1,2,3-triazole
  • Ethyl 3,5-dimethyl-4-(2-nitrobenzoyl)-1H-pyrrole-2-carboxylate
  • 1,2,3,4,5,6,7,8-Octahydro-I+/--methyl-I+/--phenyl-4-acridinemethanol
  • Methyl (I(3)R)-I(3)-amino-4-fluoro-2-hydroxy-5-nitrobenzenebutanoate
  • 1-(3,5-Dimethoxypyridin-4-yl)-2-(methylamino)ethan-1-one
  • Methyl (3Z)-3-(2-methoxy-2-oxoethylidene)-2-pyrrolidineacetate
  • Methyl 2-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-3-yl)amino]benzoate
  • Tert-butyl 4-[3-(1-hydroxycyclopropyl)propyl]piperazine-1-carboxylate
  • 6-[(2,4-Dichlorophenyl)methyl]-1,2,4-triazine-3,5(2H,4H)-dione
  • 3,4-Dihydro-3,3-dimethyl-2-(phenylmethyl)-1(2H)-isoquinolinone
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.