7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine
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Names
[ CAS No. ]:
84201-40-1
[ Name ]:
7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine
[Synonym ]:
7-methyl-6,8-dimethylthio-pyrrolo<1,2-a>pyrazine
MIII
Mbmtpp
6,8-dimethylthio-7-methylpyrrolo <1,2-a> pyrazine
Metabolite III
Chemical & Physical Properties
[ Density]:
1.25g/cm3
[ Molecular Formula ]:
C10H12N2S2
[ Molecular Weight ]:
224.34600
[ Exact Mass ]:
224.04400
[ PSA ]:
67.90000
[ LogP ]:
3.08650
[ Index of Refraction ]:
1.656
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Clin. Pharmacol. Ther. 88(3) , 360-8, (2010)
Oltipraz is a potential candidate drug for the treatment of liver fibrosis (LF) and liver cirrhosis (LC). The pharmacokinetics of oltipraz and its major rearranged metabolite (7-methyl-6,8-bis(methylt...
Mol. Pharmacol. 48(1) , 15-20, (1995)
Oltipraz, an inhibitor of human immunodeficiency virus type 1 replication in vitro (ED50 approximately 10 microM), undergoes extensive metabolism in vivo. Most of the orally administered drug undergoe...