(S)-1-tert-Butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate

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Names

[ CAS No. ]:
84348-39-0

[ Name ]:
(S)-1-tert-Butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate

[Synonym ]:
2-Methyl 1-(2-methyl-2-propanyl) (2S)-4-methylene-1,2-pyrrolidinedicarboxylate
1-O-tert-butyl 2-O-methyl (2S)-4-methylidenepyrrolidine-1,2-dicarboxylate
1,2-Pyrrolidinedicarboxylic acid, 4-methylene-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
302.0±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H19NO4

[ Molecular Weight ]:
241.284

[ Flash Point ]:
136.4±27.9 °C

[ Exact Mass ]:
241.131409

[ PSA ]:
55.84000

[ LogP ]:
1.49

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.488

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyltriphenylphosphonium bromide
  • Boc-4-oxo-Pro-OMe
  • N-t-BOC-4-Methylene-L-proline
  • methyl iodide
  • trimethylaluminum
  • Chloroiodomethane
  • methylidene triphenyl phosphorane
  • (Trimethylsilyl)diazomethane
  • methyl triphenylphosphonium bromide
  • diazomethane

DownStream

  • N-t-BOC-4-Methylene-L-proline
  • (S)-5-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid
  • (S)-5-tert-butyl 6-methyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate
  • L-Proline, 4-methylene-, methyl ester (9CI)

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • acetic acid, tert-butyl N-(1-carbamimidoylcyclopentyl)carbamate
  • 2-(1-methyl-1H-pyrazol-4-yl)-5H,6H,7H,8H-imidazo[1,2-a]pyridin-3-amine hydrochloride
  • 4-(piperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one hydrochloride
  • methyl({[2-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,2-a]pyridin-6-yl]methyl})amine dihydrochloride
  • 4-(Piperidin-4-yl)benzene-1-sulfonamide hydrochloride
  • 4-{[(6-chloro-1,3-benzothiazol-2-yl)amino]methylene}-2-(3,4-dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
  • methyl 2-amino-3-(1H-1,3-benzodiazol-1-yl)-2-methylpropanoate dihydrochloride
  • 2-(1-hydroxy-2-methylpropan-2-yl)-1H-1,3-benzodiazole-5-carboxylic acid hydrochloride
  • 5-(((6-methylbenzo[d]thiazol-2-yl)amino)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
  • [4-Bromo-2-(3,4-dichlorophenoxy)phenyl]methanamine hydrochloride
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