Astragaloside IV

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Names

[ CAS No. ]:
84687-43-4

[ Name ]:
Astragaloside IV

[Synonym ]:
Astragalus Polysaccharides
(3β,6α,9β,16β,20R,24S)-16,25-Dihydroxy-3-(β-D-xylopyranosyloxy)-20,24-epoxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside
ASTRAGALOSIDE
Astrasieversianin XIV
Astragalus extract
Astragaloside IV
β-D-Glucopyranoside, (3β,6α,9β,16β,20R,24S)-20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl
cyclosieversioside F
cyclosiversioside F
MFCD07368617

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
895.7±65.0 °C at 760 mmHg

[ Melting Point ]:
295-296ºC

[ Molecular Formula ]:
C41H68O14

[ Molecular Weight ]:
784.970

[ Flash Point ]:
495.5±34.3 °C

[ Exact Mass ]:
784.460938

[ PSA ]:
228.22000

[ LogP ]:
1.96

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.621

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

[Protective effect and mechanism of astragaloside IV on oxidative stress injury of mesangial cells].

Zhongguo Zhong Yao Za Zhi 38(5) , 725-30, (2013)

To study the protective effect of astragaloside IV (AS IV) on H2O2 induced human mesangial cells (HMC), and further explore its molecular mechanism.The cultured mesangial cells were divided into 5 gro...

Astragaloside IV inhibited the activity of CYP1A2 in liver microsomes and influenced theophylline pharmacokinetics in rats.

J. Pharm. Pharmacol. 65(1) , 149-55, (2013)

With the growing popularity of herbal and natural medicinal products, attention has turned to possible interactions between these products and pharmaceutical drugs. In this study, we examined whether ...

Astragaloside IV inhibits renal tubulointerstitial fibrosis by blocking TGF-β/Smad signaling pathway in vivo and in vitro.

Exp. Biol. Med. (Maywood.) 239(10) , 1310-24, (2014)

Astragaloside IV (AS-IV) is a major active ingredient from Radix astragali, which has been considered as a renoprotective agent; however, its molecular mechanisms are unclear. Thus, we designed to inv...


More Articles

Related Compounds

  • Astragaloside IV
  • Isoastragaloside IV
  • astragaloside V
  • Astragaloside I
  • astragaloside VIII
  • astragaloside VIII methyl ester
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