2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(p-difluoromethoxyphenyl)-1,4-dih ydropyridine

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Names

[ CAS No. ]:
84761-71-7

[ Name ]:
2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(p-difluoromethoxyphenyl)-1,4-dih ydropyridine

Chemical & Physical Properties

[ Density]:
1.242g/cm3

[ Boiling Point ]:
455.5ºC at 760 mmHg

[ Molecular Formula ]:
C18H19F2NO5

[ Molecular Weight ]:
367.34400

[ Flash Point ]:
229.3ºC

[ Exact Mass ]:
367.12300

[ PSA ]:
73.86000

[ LogP ]:
3.19760

[ Index of Refraction ]:
1.509

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7969600
CHEMICAL NAME :
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-(difluoromethoxy)phenyl)-2,6-dimethy l-, dimethyl ester
CAS REGISTRY NUMBER :
84761-71-7
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H19-F2-N-O5
MOLECULAR WEIGHT :
367.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Vascular - regional or general arteriolar or venous dilation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,817,1982

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • Ethyl 2-formylquinoline-6-carboxylate
  • (3,5-Dichlorophenyl)(2-methylpiperazin-1-yl)methanone hydrochloride
  • 6-Bromo-2-[3-(1-piperidinyl)propoxy]quinoline
  • 2-(2-aminoethoxy)-N-[5-(2,3-dihydro-1,4-benzodioxine-6-amido)-2-methylphenyl]quinoline-6-carboxamide
  • 3-Ethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
  • 6-Bromo-2-(1-methoxyethyl)quinoline
  • N-(2-Amino-1-cyclohexylethyl)-3-(1,2,4-triazol-1-yl)benzamide;dihydrochloride
  • (4-Ethylpiperazin-1-yl)(piperidin-4-yl)methanone dihydrochloride
  • 2-(3-Bromophenyl)-2-oxetanemethanol
  • 4-({[(4-Fluorophenyl)methyl]amino}methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
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