Fmoc-Glu-OtBu

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Names

[ CAS No. ]:
84793-07-7

[ Name ]:
Fmoc-Glu-OtBu

[Synonym ]:
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
Fmoc-L-Glutamicacid1-tert-butylester
(4S)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
(2S)-5-tert-Butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester
Fmoc-L-Glu-O-t-Bu
(4S)-5-tert-Butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
FMOC-GLU-OBUT
Fmoc-Glu-OtBu
L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
MFCD00065648
N-α-FMOC-L-glutamic acid α-tert-butyl ester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
638.1±55.0 °C at 760 mmHg

[ Melting Point ]:
110 °C

[ Molecular Formula ]:
C24H27NO6

[ Molecular Weight ]:
425.474

[ Flash Point ]:
339.7±31.5 °C

[ Exact Mass ]:
425.183838

[ PSA ]:
101.93000

[ LogP ]:
5.26

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34:Causes burns.

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • H-Glu-OtBu
  • Fmoc-Osu
  • (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanedioic acid 5-benzyl ester 1-tert-butyl ester
  • Fmoc-Glu(OBzl)-OH
  • L-glutamic acid
  • 9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate
  • Isobutylene

DownStream

  • H-Glu-OtBu
  • Fmoc-glu(osu)-otbu
  • H-Glu(Glu-OH)-OH
  • L-Glutamic acid, N-[N-[N-[N-[4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-.gamma.-gluta myl]-L-.gamma.-glutamyl]-L-.gamma.-glutamyl]-

Related Compounds

  • Fmoc-Glu(OtBu)-OH-15N
  • Fmoc-Glu(OtBu)-OMe
  • FMOC-GLU(OTBU)-N-CARBOXYANHYDRIDE
  • Fmoc-Glu(OtBu)-OPfp
  • Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH
  • Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH
  • 1-[1-(5-Fluoropyrimidin-4-yl)piperidin-4-yl]pyrrolidin-3-ol
  • 1-{1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl}pyrrolidin-3-ol
  • 5-Chloro-6-[4-[2-(hydroxymethyl)pyrrolidin-1-yl]piperidin-1-yl]pyridine-3-carbonitrile
  • 4,6-dimethyl-2-(4-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}piperidin-1-yl)pyrimidine
  • 2-Cyclopropyl-1-[4-({[6-(trifluoromethyl)pyridin-2-yl]oxy}methyl)piperidin-1-yl]ethan-1-one
  • (5-Fluoropyridin-3-yl)-[3-[(6-methylpyridin-2-yl)oxymethyl]piperidin-1-yl]methanone
  • 4-Ethyl-5-fluoro-6-(3-{[(2-methylpyridin-4-yl)oxy]methyl}piperidin-1-yl)pyrimidine
  • 2-{[1-(1,3-Thiazole-4-carbonyl)piperidin-3-yl]methoxy}pyridine-4-carbonitrile
  • 2-{[1-(1,3-Thiazole-4-carbonyl)piperidin-3-yl]methoxy}-3-(trifluoromethyl)pyridine
  • 2-(4-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}piperidin-1-yl)-6-(trifluoromethyl)pyridine
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