Gaboxadol hydrochloride

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Names

[ CAS No. ]:
85118-33-8

[ Name ]:
Gaboxadol hydrochloride

[Synonym ]:
Gaboxadol hydrochloride
Isoxazolo[5,4-c]pyridin-3(2H)-one, 4,5,6,7-tetrahydro-, hydrochloride (1:1)
4,5,6,7-Tetrahydro[1,2]oxazolo[5,4-c]pyridin-3(2H)-one hydrochloride (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
295.7ºC at 760 mmHg

[ Melting Point ]:
236 °C

[ Molecular Formula ]:
C6H9ClN2O2

[ Molecular Weight ]:
176.601

[ Flash Point ]:
132.6ºC

[ Exact Mass ]:
176.035248

[ PSA ]:
58.03000

[ LogP ]:
0.74440

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
NY3396800

Articles

Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.

J. Neurosci. 34(31) , 10361-78, (2014)

The enteric nervous system (ENS) provides the intrinsic neural control of the gastrointestinal tract (GIT) and regulates virtually all GI functions. Altered neuronal activity within the ENS underlies ...

Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in mice.

Psychopharmacol. Ser. 232(8) , 1415-26, (2015)

Allopregnanolone (ALLO) is an endogenous neuroactive steroid thought to alter the reinforcement value of alcohol (ethanol) due to its actions as a positive modulator of the GABAA receptor (GABAAR). Ex...

Effects of gaboxadol on the expression of cocaine sensitization in rats.

Exp. Clin. Psychopharmacol. 24 , 131-41, (2016)

Behavioral sensitization to psychostimulants is associated with changes in dopamine (DA), glutamate, and GABA within the mesocorticolimbic and nigrostriatal DA systems. Because GABAA receptors are hig...


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Related Compounds

  • gaboxadol
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