Cogentin
Suppliers
Names
[ CAS No. ]:
86-13-5
[ Name ]:
Cogentin
[Synonym ]:
Benaztropine
benzotropine
exo-Benztropine
tropine benzohydryl ether
Chemical & Physical Properties
[ Density]:
1.11g/cm3
[ Boiling Point ]:
409ºC at 760 mmHg
[ Molecular Formula ]:
C21H25NO
[ Molecular Weight ]:
307.42900
[ Flash Point ]:
120.1ºC
[ Exact Mass ]:
307.19400
[ PSA ]:
12.47000
[ LogP ]:
4.35570
[ Index of Refraction ]:
1.604
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YM3100000
- CHEMICAL NAME :
- 1-alpha-H,5-alpha-H-Tropane, 3-alpha-(diphenylmethoxy)-
- CAS REGISTRY NUMBER :
- 86-13-5
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H25-N-O
- MOLECULAR WEIGHT :
- 307.47
- WISWESSER LINE NOTATION :
- T56 A ANTJ A1 GOYR&R -ALL ALPHA
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,215,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,215,1961 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3957 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 103 (estimated) No. of Female Employees: 52 (estimated)